Molecular Research in Prostate Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 607
Special Issue Editor
Interests: prostate cancer; cell signaling; cell proliferation; cell migration/invasion
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The focus of the Special Issue will be on changes in cell signaling mechanisms that are involved in cell proliferation, migration, and invasion in prostate cancer cells during different stages of cancer progression. For example, TGFβ signaling plays critical roles during different stages of prostate cancer development. In the earlier stages of cancer development, TGFβ acts as a tumor suppressor by inhibiting cell proliferation and maintaining differentiation. In the later stages, the cancer cells develop resistance to these inhibitory effects of TGFβ on cell proliferation while maintaining the other components of TGFβ signaling. In these cells, TGFβ acts as a tumor promoter by inducing epithelial to mesenchymal transformation (EMT), cell migration, invasion and metastasis, and immune suppression. The cellular and molecular mechanisms involved in these varied effects of TGFβ are not fully understood. These mechanisms may involve reorganization and/or alterations of intracellular signaling cascades during different stages of cancer progression, resulting in altered cellular responses. This Special Issue will focus on these and other similar signaling pathways that may be altered and play differential roles during different stages of prostate cancer development and progression.
Prof. Dr. Shafiq Khan
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cell proliferation
- cell migration and invasion
- metastasis
- growth factor
- TGFβ
- cell signaling
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
