Revolving from Hypertension to Cardiovascular Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 4008
Special Issue Editor
2. IRCCS San Raffaele, Via della Pisana 235, 00163 Rome, Italy
Interests: hypertension; heart failure; neurohormonal systems; cardiovascular prevention
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hypertension is the most common modifiable risk factor for cardiovascular (CV) disease and death. Strategies for lowering blood pressure (BP) significantly reduce the development of organ damage and contribute to the prevention of major CV events.
Although a great deal of progress has been made in BP management, clinical decision-making, better adherence to guidelines and patient engagement, and adequate BP control is still insufficiently achieved in a proportion of subjects.
New drug classes such as vasopeptidases, aldosterone synthase, and soluble epoxide hydrolase inhibitors; agonists of natriuretic peptide A and vasoactive intestinal peptide receptor 2; novel mineralocorticoid receptor antagonist inhibitors of aminopeptidase A, dopamine β-hydroxylase, and intestinal Na+/H+ exchanger 3; agonists of components of the angiotensin-converting enzyme 2/angiotensin(1–7)/Mas receptor axis endothelin receptor; and antagonists and vaccines against angiotensin II and its type 1 receptor are being tested in preclinical studies and are in phase II and III trials.
The Special Issue, “Revolving From Hypertension to Cardiovascular Disease", aims to provide a research platform for a collection of the latest original and review articles that cover new insight into the biological mechanisms that are involved in the pathogenesis of hypertension, with the hopes of representing potential future therapeutic targets.
Prof. Dr. Massimo Volpe
Guest Editor
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Keywords
- hypertension
- blood pressure
- cardiovascular disease
- molecular mechanisms of hypertension
- antihypertensive drugs
- hypertension-mediated organ damage
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