Special Issue "Proteomics Analysis in Biomarker Discovery"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (10 February 2021).
Interests: proteome; secretome; biomarkers; molecular mechanisms of diseases; GPCRs
Interests: proteomics; posttranslational modification; cancer; biomarkers
Special Issues and Collections in MDPI journals
Early and accurate diagnosis is pivotal to achieving successful treatment of complex and often fatal diseases such as cancer and autoimmune, cardiovascular, and neurodegenerative diseases. In clinical practice, the prediction outcomes, and responses to treatment, is also considered of great importance. For a long time, some blood biomarkers have been used as tools for diagnosis and follow-up purposes. Nevertheless, currently available biomarkers, which are far from being comprehensive, often lack specificity, and thus in the last decade omics-based technologies have been extensively used for biomarker discovery. Proteomics analysis of various body fluids such as plasma, serum, and saliva, and tissue specimens, has largely contributed to the detection of new potential biomarkers for various diseases. The constant advance of mass spectrometry techniques has been essential to this ongoing process. In recent years, proteomics analysis of cell culture secretome, cell, and body fluid exomes has also been implemented, leading to new discoveries that have shed light on cell communications in pathological conditions such as cancer. Particularly, exosome protein cargos appear to reflect the pathological state of the originated cells and thus can represent enriched sources of pivotal biomarkers.
Scientists working in the field of proteomics analysis applied to biomarkers discovery for human diseases are encouraged to consider this Special Issue for submitting recent research and review articles. While research dealing with innovative approaches is particularly welcome, proteomics investigations that highlight the molecular mechanisms of diseases are also of interest.
Dr. Maria Rosa Mazzoni
Dr. Laura Giusti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mass spectrometry