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Special Issue "PPARs in Metabolic Regulation: Implications for Health and Disease"
Deadline for manuscript submissions: 31 March 2020.
Interests: nuclear receptor superfamily, gene regulation and gene expression profiling, metabolic regulations, development, skin and wound healing, cancer, liver physiology, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), adipose tissue, muscle and exercise, gut, microbiota, inter-organ cross-talk, nutrition, nutrigenetics and nutrigenomics
Special Issues and Collections in MDPI journals
Special Issues and Collections in MDPI journals
This Special Issue is the continuation of our previous special issue "PPARs in Cellular and Whole Body Energy Metabolism".
According to the World Health Organization, noncommunicable diseases (NCDs) kill 41 million people each year, equivalent to more than 70% of all deaths worldwide. In general, these diseases are of long duration and are the result of a combination of genetic, physiological, lifestyle (nutrition, sedentarity), and environmental factors. There is mounting evidence that a group of related transcription factors, the nuclear receptors called peroxisome proliferator-activated receptors (PPARs), are involved in some of these chronic diseases, such as obesity, diabetes, cardiovascular diseases, and cancer. PPAR activity is modulated not only by fatty acids and their derivatives, but also by drugs such as thiazolidinediones and fibrates, which has instigated an extraordinary research effort for understanding the roles of PPARs in health and disease, more particularly through metabolic regulation. This Special Issue of IJMS will cover the latest developments in the physiological functions of PPARs in all organs, including their responses to nutrition and physical activity. It will explore processes regulated by PPARs, which are implicated in cellular and whole-organism metabolism. How key roles of PPARs in healthy and diseased organisms can be modulated to maintain or improve the optimal health of individuals and populations is of foremost interest.
Prof. Dr. Walter Wahli
Ms. Rachel Tee
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Peroxisome Proliferator-Activated Receptors (PPARs)
- Energy homeostasis
- Metabolic regulations
- Organ cross-talk
- Lipids and carbohydrates
- Metabolic diseases
- Cancer and reprogramming of energy metabolism
- Systems biology
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: PPARb/d's role in ocular angiogenesis
Authors: Xiaomeng Wang, et al.
Title: PPARs as nutrient sensors in the liver OR PPARs as lipid metabolism regulators in the liver
Authors: Naoki Tanaka, et al.
Title: Interaction Analysis of PPARa with EPA/DHA based on first-principles calculations
Authors: Hitoshi Shimano, et al.
Title: Transcriptional regulation by PPARb/d
Authors: Rolf Müller, et al.
Title: A molecular footprint of resilience potentially defines the colitis-cancer border
Authors: Pallavi R. Devchand, Michael Dicay, Gordon W. McKnight and John L.Wallace
Title: Role of PPARs in ethanol metabolism and alcoholic livers disease
Authors: Andrea Galli, et al.
Title: Multifaceted phenotype of PPARgamma null mice: new insights on adipose tissue and PPARg actions
Authors: Federica Gilardi