The Role of Secondary Metabolites in Inflammation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (15 February 2023) | Viewed by 2499
Special Issue Editor
Special Issue Information
Dear Colleagues,
Secondary (or specialized) metabolites is a very broad term for a variety of small molecules that often have profound physiological effects. Common for many of these molecules is that they regulate inflammation, and often the interaction between primary metabolism and inflammation, but the exact mechanism is often poorly understood. Some secondary metabolites are well-known hormones, such as those originating from steroid biosynthesis (glucocorticoids, sex hormones, etc.) or from amino acid metabolism (serotonin, dopamine, etc.), and other well-known molecules, such as kyneurins and prostaglandins. Lesser-known secondary metabolites that are also endogenously generated are the classical plant hormones abscisic acid (ABA), cytokinins (CKs), indole-3-acetic acid (Auxin), and salicylic acid (SA). For many of these molecules, elucidating their roles is further complicated by the fact that they may originate from several different sources, such as endogenous biosynthesis, microbiota, or nutrition.
We warmly welcome submissions, including original papers and reviews, investigating the signaling effects from secondary metabolites and their effect on inflammation and inflammation-related diseases.
Dr. Jens Staal
Guest Editor
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Keywords
- inflammation
- immunometabolism
- specialized metabolism
- secondary metabolites
- small molecules
- hormones
- homeostasis
