Special Issue "Molecular Pathology of Lung and Thoracic Cancers"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 March 2020).
Interests: pancreatic cancer; colorectal cancer; lung cancer; molecular biomarkers; liquid biopsy; proteomics; autoantibody; microRNA; long non-coding RNA; post-translational modifications
Lung cancer is the most common type of thoracic cancer, making the most lethal cancer worldwide. Despite improvements in early detection, surgical treatment, systemic therapy, and radiotherapy, most patients with thoracic cancer are diagnosed at an advanced stage and have a poor prognosis.
Recent advances in molecular profiling technologies have dramatically deepened our understanding of cancer biology, and opened up novel approaches to detect molecular alteration as biomarkers in DNA, RNA, microRNA/long non-coding RNA, proteins, metabolites, exosomes, and circulating tumor cells, using a variety of biospecimens, such as tissue, blood, urine, sputum, and saliva. Molecular biomarkers can be used in multiple clinical settings, including risk assessment, screening, early detection, differential diagnosis, determination of prognosis, therapy selection, prediction of response/toxicity to treatment, and monitoring of reccurence/progression, and have potential to bring about a paradigm shift in current practice and improvement of lung cancer survival.
The scope of this Special Issue is to attract original research as well as review articles describing all aspects of tissue- or biofluid-based molecular biomarkers of lung cancer and other types of thoracic cancer, including thymic tumors and mesothelioma. Potential topics include but are not limited to the following: discovery and/or validation of diagnostic, prognostic, and therapeutic molecular biomarkers; method development for data acquisition and analysis; statistical and bioinformatic approaches to biomarker discovery and development of omics-based signatures; and integration and development of biomarker model.
Dr. Ayumu Taguchi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- lung cancer
- thoracic cancer
- precision medicine
- molecular biomarkers
- molecular pathology
- liquid biopsy
- DNA mutation
- DNA methylation
- genome-wide association studies
- single nucleotide polymorphism
- gene expression
- in situ hybridization
- long non-coding RNA
- post-translational modifications
- circulating tumor cells
- cell lines
- mouse models