Molecular Mechanisms of Neurological and Psychiatric Disease: A Decade of Progress

Dear Colleagues,

Until several decades ago, psychological and behavioural interventions were the primary treatments for mental health disorders.

Thanks to modern psychopharmacology, medications are accepted to treat more psychiatric disorders.

Unfortunately, the mechanism behind many medications is unknown. Several therapeutic approaches are derived from neurological pathologies.

Psychiatric disorders are often present in various neurological diseases like Alzheimer's and Parkinson's disease, epilepsy, migraine, essential tremors, and stroke. Depression, anxiety disorders, and cognitive impairment are the most common comorbid diagnoses in neurological diseases. It is important to note that comorbidities are frequently overlooked due to common neurochemical mechanisms or a loss of previous functioning levels.

Moreover, some medications may have drawbacks, including drug interactions, side effects, and low effectiveness. In light of these, evidence has become essential to characterize the molecular mechanism of neurological and psychiatric disease to ensure the best treatments are utilized.

The colossal effort of researchers to increase the knowledge of many psychiatric and neurological disorders in the last few decades has helped us to understand not only the developmental stages of many diseases but, principally, the mechanism of action of medication on specific molecular targets.

This Special Issue aims to collect original research articles (regular and rapid communication) and reviews on the underlying molecular mechanisms of psychiatric and degenerative diseases and the therapeutic properties of substances, including those derived from plants.

Dr. Martina Montanari (martimonty@gmail.com) is the Guest Editor Assistant of this Special Issue. Please feel free to contact us or Ms. Martina Montanari for details about the issue.

Dr. Giuseppina Martella
Guest Editor

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