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Special Issue "Quo Vadis Cancer Research? On Molecular Mechanisms and Drug Discovery"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 31 July 2021.

Special Issue Editor

Dr. Silvie Rimpelova
Website1 Website2
Guest Editor
University of Chemistry and Technology Prague, Department of Biochemistry and Microbiology, Technicka 5, 16628 Prague 6, Czech Republic
Interests: anticancer activity; drug discovery; antimicrobial activity; plant secondary metabolites; bioactive compounds; super-resolution fluorescence microscopy; photodynamic therapy; multimodal compounds; theranostics; mitochondrial sensors; biomaterials

Special Issue Information

Dear colleagues,

In cancer research, an immense amount of interdisciplinary information has already been gathered over the decades. The remaining gaps in the knowledge on cancer diseases at the cellular and molecular levels are being filled on a daily basis as novel research methods and novel anticancer drugs emerge. In addition, using old and already-approved drugs for different indications, such as cancer, has recently gained increased attention from the scientific community in so-called drug repurposing. Moreover, there is also a very common concept of developing compounds with multiple functionalities—from combining diagnostics with therapy (theranostics) to specific targeting, and photodynamic therapy to immunogenic cell death induction. All of these approaches will hopefully enable the early detection of cancer and combating of this disease with minimal side-effects.

The aim of this Special Issue “Quo Vadis Cancer Research? On Molecular Mechanisms and Drug Discovery” is to underline the advances and the most recent discoveries and progress in all fields of science dealing with cancer; its molecular substance; known, and also possible, synthetic and semisynthetic inhibitors; their structure–activity relationships; in silico modeling; theranostics; cancer biomarkers; and beyond. Original full research articles as well as review articles on this topic from research groups all over the world are welcome in order to disseminate the scientific knowledge in these uneasy times of SARS-CoV-2. Researchers working in the fields of cancer research, imaging, drug discovery and related disciplines are encouraged to publish their recent findings in this Special Issue of the International Journal of Molecular Sciences.

Dr. Silvie Rimpelova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Molecular biology of cancer
  • Resistance
  • In silico modeling
  • Drug discovery
  • Synthesis and semisynthesis
  • Anticancer potential
  • Structure–activity relationship
  • Biological activity
  • Biomarkers
  • Diagnosis and therapy (theranostics)
  • Targeted therapy
  • Antibodies

Published Papers

This special issue is now open for submission.
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