Quo Vadis Cancer Research? On Molecular Mechanisms and Drug Discovery

Dear colleagues,

In cancer research, an immense amount of interdisciplinary information has already been gathered over the decades. The remaining gaps in the knowledge on cancer diseases at the cellular and molecular levels are being filled on a daily basis as novel research methods and novel anticancer drugs emerge. In addition, using old and already-approved drugs for different indications, such as cancer, has recently gained increased attention from the scientific community in so-called drug repurposing. Moreover, there is also a very common concept of developing compounds with multiple functionalities—from combining diagnostics with therapy (theranostics) to specific targeting, and photodynamic therapy to immunogenic cell death induction. All of these approaches will hopefully enable the early detection of cancer and combating of this disease with minimal side-effects.

The aim of this Special Issue “Quo Vadis Cancer Research? On Molecular Mechanisms and Drug Discovery” is to underline the advances and the most recent discoveries and progress in all fields of science dealing with cancer; its molecular substance; known, and also possible, synthetic and semisynthetic inhibitors; their structure–activity relationships; in silico modeling; theranostics; cancer biomarkers; and beyond. Original full research articles as well as review articles on this topic from research groups all over the world are welcome in order to disseminate the scientific knowledge in these uneasy times of SARS-CoV-2. Researchers working in the fields of cancer research, imaging, drug discovery and related disciplines are encouraged to publish their recent findings in this Special Issue of the International Journal of Molecular Sciences.

Dr. Silvie Rimpelova
Guest Editor

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