Molecular Research on Vascular Disease: Current Status and Future Directions

Dear Colleagues,

Historically, the vasculature has been described as essential in maintaining cellular homeostasis. Anatomically, the vasculature is divided into micro- and macrovasculature systems according to the diameter of the relevant vessel. Its function includes the transportation of oxygen and nutrients towards the tissues and the degradation of cellular metabolism products. Over the last few decades, the roles of the vasculature have been expanded and include different processes such as organ development, inflammatory processes, and tissue regeneration.

Vascular disease is considered to be both a cause and a consequence of the derangement of the micro- and/or macrovasculature in terms of function and morphology. A variety of factors, including physical stimulation, toxins, concurrent related diseases, and aging, induce pathophysiological processes, such as inflammation and oxidative stress, that exert detrimental effects on vascular function and structure. Several systemic diseases affect the vasculature, including cardiovascular diseases, hematological disorders, and chronic inflammatory diseases.

This Special Issue aims to collect original studies and comprehensive reviews on vascular disease at the molecular level. More specifically, it aims to provide novel insights on the molecular mechanisms, diagnosis, and treatment of vascular disease and related syndromes.

Dr. Eleni Gavriilaki
Dr. Panagiota Anyfanti
Guest Editors

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• vascular disease
• microvasculature
• vascular inflammation
• vascular dysfunction