Special Issue "Regenerative Medicine for Peripheral Nerve Injury: Recent Advances, Emerging Therapies and Future Directions"
Deadline for manuscript submissions: closed (31 December 2021).
Interests: peripheral nerve regeneration; translational research; biomaterials; tissue engineering; neuregulin1/ErbB system; stereology
Interests: mechanosensing; nano/microstructured materials; biomaterials; peripheral nerve regeneration; neural cells; cell migration; nanofabrication; nanobiotechnologies
Peripheral nerves are widely spread throughout the body and can be damaged in several ways: as a result of a car crash, domestic or sport falls, work accidents, war wounds, or as a consequence of direct surgical trauma, anesthetic interventions, or radical tumor resection (iatrogenic injuries).
Injury to peripheral nerves represents a major cause of morbidity and negatively impacts the quality of life of an increasing number of patients, bringing about physical disability and total or partial loss of their productive activities with important related social and economic consequences.
Nowadays, there are no repair or reconstruction techniques that can ensure the full restoration of sensorimotor functions of patients following severe nerve injuries. Therefore, the repair, reconstruction, and regeneration of peripheral nerve injuries represents a major field where innovative therapies should be investigated.
In recent years, there have been many advances in different areas of regenerative medicine, including reconstructive microsurgery techniques, tissue engineering, nanomedicine, material science, regenerative 2/3D scaffolds (microfabrication techniques, microstructured substrates, functionalization), gene therapy, stem cell biology, and cell transplantation.
This Special Issue of IJMS will focus on recent advances in regenerative medicine for peripheral nerve injury, both in basic and translational research. We invite researchers to contribute by submitting both original research articles and reviews of the literature. We are interested in articles that outline the latest advances in nerve regeneration research as well as that explore novel therapies and approaches for promoting peripheral nerve regeneration (e.g., new biomaterials and their functionalization/nano–microstructuration, 2/3D engineered scaffolds and innovative fabrication techniques, innovative gene therapy approaches, delivery of growth factors, and involvement of new molecules in the process of nerve regeneration). Interdisciplinary approaches, even computational, that bring together different aspects of regenerative medicine are welcome.
Dr. Giulia Ronchi
Dr. Ilaria Tonazzini
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Peripheral nerve injury and regeneration
- Regenerative medicine
- Schwann cells
- Gene therapy
- Cell therapy
- Growth factors
- Translational research
- Stem cells
- 2/3D scaffolds
- Nano–microstructured materials
- 3D printing