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Artificial Intelligence and Immune-Mediated Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 386

Special Issue Editors

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Guest Editor
Head of Allergology and Clinical Immunology Unit, Department of Internal Medicine, University of Genoa and San Bartolomeo Hospital, Sarzana, Italy
Interests: immunodeficiency; autoimmunity; neuro-endocrino-immunology; pharmacogenomics; soluble molecules; immune-mediated diseases; allergies; vaccines
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, 98125 Messina, Italy
Interests: inflammatory mediators; the citokine network (interleukins, chemokines, adhesion molecules, lipoxines); the oxidative stress in various areas of clinical immunology; allergy; oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Artificial intelligence (AI) is assuming an ever-increasing role and is currently being applied in the biomedical field. It is presumable that it will play a leading role in the future of medicine. Machine learning (ML) represents one of the most exciting research fields in AI. However, ML algorithms can use a large amount of data and extract meaningful results from it, thus, giving the computer the ability to learn without being explicitly programmed to do so. ML can help to classify patients, predict future outcomes, and even personalize patient treatment. Specifically, in the field of immune-mediated diseases, the application of AI can support the diagnosis of systemic immune-mediated diseases, which include, among others, systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, Sjogren's syndrome, mixed connective tissue disease and undifferentiated connective tissue disease.

It is foreseeable that the use of AI could allow the early prediction of the involvement of viscera (lungs, heart, kidneys, gastrointestinal tract, etc.). For example, as already demonstrated, the application of AI in patients with systemic sclerosis can lead to the early detection of interstitial lung disease, ILD, anticipating the functional signs shown by spirometry and pH impedancemetry, allowing us to broaden the use of high-definition chest CT required in international guidelines.

This Special Issue aims to collect and analyze the most recent scientific evidence in support of AI in the diagnosis of systemic immune-mediated diseases. Both review and research papers are welcome. Please note that pure clinical or model studies are unsuitable for this journal, but clinical submissions with biomolecular studies are welcome.

Dr. Giuseppe Murdaca
Prof. Dr. Sebastiano Gangemi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • artificial intelligence (AI)
  • AI and systemic/organ-specific immune-mediated diseases
  • AI and autoimmunity
  • AI and immune-related diseases
  • AI and cytokines
  • AI and signaling molecules and their receptors

Published Papers

There is no accepted submissions to this special issue at this moment.
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