The Roles of Circular RNAs in Immune Responses and Immune Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1910
Special Issue Editors
Interests: immunodeficiency; autoimmunity; neuro-endocrino-immunology; pharmacogenomics; soluble molecules; immune-mediated diseases; allergies; vaccines
Special Issues, Collections and Topics in MDPI journals
Interests: mediators of inflammation, cytokines, and biomarkers of oxidative stress; immunosenescence; immunogenetics; epigenetics; application of machine learning and deep learning in various fields of medicine
Special Issues, Collections and Topics in MDPI journals
Interests: blood disease; hematological malignancies; myeloma; lymphoma; leukemia; platelets; hematology
Special Issues, Collections and Topics in MDPI journals
Interests: immunosenescence
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Numerous enzymes, transcription factors, signal transducers and membrane proteins contribute to control immune system activity. The “transcriptional machine” of eukaryotic cells is a complex system, composed not only of coding material as messenger RNAs (mRNAs) but also of non-coding elements, grouped together in the set of non-coding RNAs (ncRNAs). According to their structure, circular RNAs (circRNAs) can be divided into several groups such as exonic circRNAs (EcircRNAs) made by exons, intronic circRNAs (IcircRNAs) made by introns, and exon–intron circRNAs (EIcircRNAs) made by both exons and introns. Recent studies demonstrate that circRNAs play a crucial role in numerous cellular functions, in gene expression in physiology, and in the pathogenesis of many immune disorders. Principal functions of circRNAs include miRNA inhibition, epithelial–mesenchymal transition and tumorigenesis. The expression of circRNAs can also be specific to the tissue. Furthermore, circRNAs were found in different types of biological samples including plasma, cell-free saliva, and exosomes. The aim of this Special Issue is to gather high-quality original research, articles, and reviews that contribute to our understanding of the roles that circRNAs play in immune-mediated diseases.
Dr. Giuseppe Murdaca
Prof. Dr. Sebastiano Gangemi
Dr. Alessandro Allegra
Dr. Francesca Paladin
Guest Editors
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Keywords
- circRNAs and immune system
- EcircRNAs and immune system
- IcircRNAs and immune system
- EIcircRNAs and immune system
- circRNAs and immune-mediated diseases
- EcircRNAs and immune-mediated diseases
- IcircRNAs and immune-mediated diseases
- EIcircRNAs and immune-mediated diseases
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