Inflammatory Signaling Pathways Involved in Gastrointestinal Diseases: Second Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 July 2025 | Viewed by 4628
Special Issue Editors
Interests: inflammatory diseases; cancer; oxidative stress; biochemical mechanisms of cell death and survival (apoptosis, necrosis, autophagy); nutraceuticals; food intolerance
Special Issues, Collections and Topics in MDPI journals
Interests: mechanisms of oxidative stress induction and main antioxidant systems; biochemical pathways of cell death and survival (apoptosis, necrosis, autophagy) in tumor cells; effects of phytocompounds in obesity reduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammation is a defensive response of the innate and adaptive immune systems against injury and/or harmful microorganisms that restores homeostasis. The importance of inflammatory signaling pathways in diseases has been recognized, and the signaling molecules implicated in these pathways are thought to be promising targets for the development of new therapeutic strategies. Many studies have demonstrated that inflammation-related signaling pathways influence the homeostasis and health of the human gastrointestinal system.
The main goal of this Special Issue is to shed light, through both original research and review articles, on the role of immune inflammatory signaling pathways in gastrointestinal inflammation and tumors, and on the latest progress in understanding the corresponding regulatory mechanisms. We also welcome research papers evaluating strategies to reduce inflammation in inflammatory gastrointestinal diseases. Moreover, this Special Issue explores the effects and mechanisms of different signaling pathways in tumors such as gastric cancer and colorectal cancer, as well as inflammatory diseases such as inflammatory bowel disease (IBD), intestinal-related sepsis, colonitis and celiac disease. Complete knowledge of the inflammatory signaling pathways could be helpful not only for the prevention but also for the novel treatment of these diseases.
Generally, pure clinical research or model studies, survey studies and correlation research are outside of the scope of IJMS. However, clinical or model studies that involve biomolecular experiments are welcomed.
This Special Issue is supervised by Dr. Diana Di Liberto and Prof. Dr. Marianna Lauricella, who are assisted by our Topical Advisory Panel Member Dr. Giovanni Pratelli (University of Palermo).
Dr. Diana Di Liberto
Prof. Dr. Marianna Lauricella
Guest Editors
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Keywords
- inflammatory signaling pathways
- gastrointestinal diseases
- gastrointestinal cancer
- inflammatory bowel disease
- colonitis
- colorectal cancer
- cytokine
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