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Synthetic Polymers for 3D Printing

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".

Deadline for manuscript submissions: closed (30 January 2024) | Viewed by 3240

Special Issue Editor


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Guest Editor
1. Professor, Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan
2. Adjunct Professor, Orthopedic Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan
Interests: bioabsorbable medical devices; drug delivery; tissue engineering; nanofibers; core-shell microspheres; polymer processing; water (gas) assisted injection molding; micro/nano-optical/electrical devices; rotational molding; ultrasonic welding; micro/nano-structure embossing
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Special Issue Information

Dear Colleagues, 

Three-dimensional (3D) printing has emerged as a versatile and innovative technology. It holds many opportunities for improving the efficiency of manufacturing processes. With cost-effective manufacturing for high productivity, 3D printing has become a leading manufacturing technology for various applications. The technology enables the fabrication of very complex shapes or geometries with high adjustability and resolution that would otherwise be impossible to construct by hand, including hollow parts or internal truss structures to reduce weight parts. This Special Issue aims to highlight the most popular academic research and industrial and commercial developments of synthetic polymers that have applications in medicine, education, architecture, etc. It also aims to explore emerging challenges and opportunities ranging from new developments of polymeric materials and 3D printing processes to new simulation and design tools and informative applications and case studies. Reports of fundamental scientific investigations are welcome, as are articles correlated to the practical applications of 3D-printed polymers in healthcare and pharmaceuticals. Both experimental and theoretical work is of interest, and theoretical papers should generally include a comparison of predictions with experimental data.

Prof. Dr. Shih-Jung (Sean) Liu
Guest Editor

Manuscript Submission Information

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Keywords

  • synthetic polymers
  • 3D printing
  • experimental and theoretical
  • process parameters
  • applications

Published Papers (2 papers)

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Research

16 pages, 3146 KiB  
Article
Anti-Adhesive Resorbable Indomethacin/Bupivacaine-Eluting Nanofibers for Tendon Rupture Repair: In Vitro and In Vivo Studies
by Yi-Hsun Yu, Chen-Hung Lee, Yung-Heng Hsu, Ying-Chao Chou, Ping-Chun Yu, Chao-Tsai Huang and Shih-Jung Liu
Int. J. Mol. Sci. 2023, 24(22), 16235; https://doi.org/10.3390/ijms242216235 - 12 Nov 2023
Cited by 1 | Viewed by 929
Abstract
The treatment and surgical repair of torn Achilles tendons seldom return the wounded tendon to its original elasticity and stiffness. This study explored the in vitro and in vivo simultaneous release of indomethacin and bupivacaine from electrospun polylactide–polyglycolide composite membranes for their capacity [...] Read more.
The treatment and surgical repair of torn Achilles tendons seldom return the wounded tendon to its original elasticity and stiffness. This study explored the in vitro and in vivo simultaneous release of indomethacin and bupivacaine from electrospun polylactide–polyglycolide composite membranes for their capacity to repair torn Achilles tendons. These membranes were fabricated by mixing polylactide–polyglycolide/indomethacin, polylactide–polyglycolide/collagen, and polylactide–polyglycolide/bupivacaine with 1,1,1,3,3,3-hexafluoro-2-propanol into sandwich-structured composites. Subsequently, the in vitro pharmaceutic release rates over 30 days were determined, and the in vivo release behavior and effectiveness of the loaded drugs were assessed using an animal surgical model. High concentrations of indomethacin and bupivacaine were released for over four weeks. The released pharmaceutics resulted in complete recovery of rat tendons, and the nanofibrous composite membranes exhibited exceptional mechanical strength. Additionally, the anti-adhesion capacity of the developed membrane was confirmed. Using the electrospinning technique developed in this study, we plan on manufacturing degradable composite membranes for tendon healing, which can deliver sustained pharmaceutical release and provide a collagenous habitat. Full article
(This article belongs to the Special Issue Synthetic Polymers for 3D Printing)
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15 pages, 9339 KiB  
Article
Novel Formulations Containing Fluorescent Sensors to Improve the Resolution of 3D Prints
by Monika Topa-Skwarczyńska, Andrzej Świeży, Dominika Krok, Katarzyna Starzak, Paweł Niezgoda, Bartosz Oksiuta, Weronika Wałczyk and Joanna Ortyl
Int. J. Mol. Sci. 2022, 23(18), 10470; https://doi.org/10.3390/ijms231810470 - 9 Sep 2022
Cited by 6 | Viewed by 1941
Abstract
Three-dimensional printing in SLA (stereolithography) and DLP (digital light processing) technologies has recently been experiencing a period of extremely rapid development. This is due to the fact that researchers recognise the many advantages of 3D printing, such as the high resolution and speed [...] Read more.
Three-dimensional printing in SLA (stereolithography) and DLP (digital light processing) technologies has recently been experiencing a period of extremely rapid development. This is due to the fact that researchers recognise the many advantages of 3D printing, such as the high resolution and speed of the modelling and printing processes. However, there is still a search for new resin formulations dedicated to specific 3D printers allowing for high-resolution prints. Therefore, in the following paper, the effects of dyes such as BODIPY, europium complex, and Coumarin 1 added to light-cured compositions polymerised according to the radical mechanism on the photopolymerisation process speed, polymerisation shrinkage, and the final properties of the printouts were investigated. The kinetics of the photopolymerisation of light-cured materials using real-time FT-IR methods, as well as printouts that tangibly demonstrate the potential application of 3D printing technology in Industry 4.0, were examined. These studies showed that the addition of dyes has an effect on obtaining fluorescent prints with good resolution. Full article
(This article belongs to the Special Issue Synthetic Polymers for 3D Printing)
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