Recent Advances in Ion Channels and Ion Channelopathies

Dear Colleagues,

Ion channels play critical roles in normal cellular function. In addition, perturbations in ion channel function can lead to the development of disease. These ion channelopathies have the capacity to affect various organ systems, including the nervous, cardiovascular, and endocrine systems, with a significant number of ion channelopathies associated with epithelial systems. Ion channels may be present in protein complexes and may control cellular function by intracellular signaling. Ion channels can affect cell function at the cell membrane or within intracellular organelles. The key to the development of therapeutics targeted toward ion channels is a clear understanding of how these proteins modulate cellular function and how dysfunction leads to pathology.

In this Special Issue, original studies on all aspects of ion channels and ion channelopathies are welcome, with a particular emphasis on molecular analyses of ion channels and the mechanism by which perturbations in function can lead to ion channelopathies.

Dr. Deanne H. Hryciw
Guest Editor

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