Arthritis: Focus on Pathologies, Symptoms and Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 953
Special Issue Editor
Interests: natural products; pharmacology; immunology; rheumatoid arthritis; medicinal plants; antioxidants; biological models; new generations of drug delivery; functional food
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Rheumatoid arthritis (RA) is a chronic, complex, immunopathogenetically mediated autoimmune disease that leads to severe destructive arthritis, affecting multiple joints with subsequent significant functional impairment, reducing the patient's quality of life, and potentially leading to disability. RA is characterized by chronic local and systemic inflammatory processes. It involves persistent synovitis with subsequent joint destruction, erosion, and deformation. Besides joint manifestations, extra-articular manifestations of the disease are not uncommon. After the onset of extra-articular symptoms, active investigation is always necessary, as they can significantly worsen the prognosis of the disease, including the patient's lifespan. Extraarticular manifestations of RA may develop during the clinical course of RA, even before the onset of arthritis. The onset of clinically evident RA is preceded by a period of preclinical RA (pre-RA). The development of pre-RA and its progression to established RA has been categorized into several different pathophysiological phases. The cause of RA is not yet fully understood. Genetic, environmental, hormonal, metabolic, immunological, and infectious factors may play a significant role. Advanced research techniques have enabled better characterization of cellular and molecular processes involved in the dysregulation of innate and acquired immune responses, with the identification of new pathways that are useful for the development of new therapeutic approaches for RA.
This Special Issue entitled Arthritis: Pathologies, Symptoms and Therapy welcomes manuscripts in the formats of research articles, short communications, case reports, and reviews. Manuscripts should focus on the research of ethiopatology of RA, its early and effective diagnosis based on well-defined symptoms and particularly on new therapeutic approaches of this serious diseases.
Dr. Katarína Bauerová
Guest Editor
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Keywords
- rheumatoid arthritis
- autoimmune
- pathogenesis
- strategies
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