Stem Cells and Regenerative Medicine: In Vitro and In Vivo Studies

Dear Colleagues,

In recent years, stem cell therapy has become a very promising and advanced scientific research topic. Stem cells have the capability to self-renew and to differentiate into several cell types, and are involved in physiological regeneration processes.

In the context of tissue injury, stem cells have gained worldwide attention because of their immense potential for immunomodulation and their therapeutic function. Stem cells can migrate to tissue injury areas to contribute to immune modulation, secrete anti-inflammatory cytokines, and hide themselves from the immune system.

With so many stem cell replacement therapies currently going through clinical trials, there is a compelling need to understand the mechanisms behind a successful therapy, and one of the critical points of their discovery is to monitor and manage stem cell migration, proliferation, differentiation, and organization in vitro as well as in vivo. In this context, the use of biomaterials to manipulate stem cells providing control of their behavior and homing has received great interest, becoming a pivotal step for the development of innovative stem cell transplantation solutions. 

This Special Issue aims to provide the latest updates on stem cells and their in vitro and in vivo applications in the regenerative medicine field, opening novel and advanced strategies for tissue-repairing processes and many other clinical applications.

Original articles, up-to-date review articles, and commentaries addressing this topic are all welcome.

Dr. Alessia Peserico
Guest Editor

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