Cell Metabolism and Small Natural Compounds (2nd Edition)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (20 January 2025) | Viewed by 10508
Special Issue Editors
Interests: mitochondria; protein purification; antioxidant activity; biomolecules extraction; agricultural waste valorization; novel food
Special Issues, Collections and Topics in MDPI journals
Interests: mitochondria; bioenergetics; ATP synthase; permeability transition pore; mitochondrial supercomplexes; cell metabolism; post-translational modifications
Special Issues, Collections and Topics in MDPI journals
Interests: nutraceuticals; mitochondria; membrane proteins; cell metabolism; cardiovascular disease; metabolic syndrome; omics sciences
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our previous Special Issue “Cell Metabolism and Small Natural Compounds”.
Cellular metabolism, and especially its dysregulation, plays a key role in the physiology of the onset of many diseases, such as cancer, diabetes, metabolic syndrome, and cardiovascular as well as neurodegenerative diseases.
Over the years, only through in-depth studies of biochemistry and molecular biology has it been possible to better understand the correlation between cellular mechanisms and various chemical mediators.
In particular, the knowledge of and research on the mechanisms that involve the alteration of energy metabolism, the overproduction of reactive oxygen species (ROS) as well as nitrogen species (RNS), the imbalance between proliferation and cell death, and the interaction between enzymes and substrates represent useful and fundamental tools with which to create new therapeutic approaches that are more effective and ensure better quality of life.
Therefore, the detailed study of potential natural mediators of cellular metabolism, both endogenous and exogenous (extracted from animal and plant sources), becomes an interesting research topic to be enriched with information. The multiplicity of bioactive molecules present in nature, which is associated with a potential therapeutic effect and increased tolerability as well as bioavailability, is an excellent alternative to synthetic drugs.
The increased knowledge of altered metabolic pathways and the ability of natural compounds to modulate them are achievements, in addition to great steps forward for science.
Given the particular historical moment in which we are living, this Special Issue aims to focus more attention of the entire scientific community on the great therapeutic potential of natural compounds, and especially on their safety for health.
In particular, we encourage the submission of original manuscripts and reviews that bring new insights as well as information on the biochemical interaction of known or novel natural compounds with cellular metabolism, in health and disease, in order to design new and innovative therapeutic approaches.
Dr. Anna Spagnoletta
Dr. Salvatore Nesci
Dr. Francesca Oppedisano
Guest Editors
Manuscript Submission Information
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Keywords
- cell metabolism
- mitochondria
- ROS
- RNS
- proliferation and cell death
- metabolic pathways
- natural compounds
- bioactive molecules
- human pathology
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