Chrononutrition, Fasting, and Aging: Exploring the Temporal Dynamics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2026
Special Issue Editors
Interests: obesity; cardiovascular disease; mediterranean diet; nutrigenetic; nutrigenomic; sleep deprivation; circadian rhythms; taste perception; aging
Special Issues, Collections and Topics in MDPI journals
Interests: precision nutrition; omics; Mediterranean diet; lifestyle; cardiovascular disease; obesity; nutrigenomics; epigenomics; metabolomics; transcriptomic; gene–diet interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chrononutrition, fasting and aging are emerging frontiers at the intersection of nutrition, circadian biology and health. Increasing evidence shows that not only what we eat but also when we eat, plays a critical role in metabolic regulation, cellular homeostasis and healthy aging. Feeding–fasting cycles are tightly synchronized with circadian rhythms, and disruption of this temporal alignment is associated with metabolic disorders, accelerated aging and increased risk of chronic disease. Time-restricted feeding and intermittent fasting have gained scientific attention for their ability to improve insulin sensitivity, promote autophagy, and modulate inflammatory pathways. Similarly, the field of chrononutrition explores how the timing of nutrient intake can optimize physiological processes and mitigate age-related decline. Together, these approaches highlight the importance of temporal dynamics in dietary interventions.
By integrating insights from molecular biology, clinical research, and population studies, this Special Issue aims to advance understanding of how eating patterns influence longevity and age-related health outcomes. Ultimately, unraveling these mechanisms could open new preventive and therapeutic strategies to promote healthy aging through personalized, time-based nutrition.
Dr. Rocío Barragán
Prof. Dr. Dolores Corella
Guest Editors
Manuscript Submission Information
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Keywords
- fasting
- chronobiology
- aging
- chrononutrition
- chronic diseases
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