RNA Modification

Dear Colleagues,

RNA modification is revealed to be an additional regulatory layer of the primary transcriptome. The major RNA modifications in the eukaryotic cells are N6-methyladenosine (m6A), 5-methylcytidine (m5C), N1-methyladenosine (m1A), inosine or pseudouridine. These modifications regulate various kinds of important physiological processes involving stress and immune responses, or epigenetic inheritance by regulating gene expression at multiple steps. They are known to be enriched in tRNAs, but recent improvement of sequence technology revealed that RNA modifications are also observed in other RNA molecules involving small RNAs or long non-coding RNAs. Thus, RNA modifications play important roles in eukaryotic genome recoding processes during environmental responses or diseases. In this Special Issue, we welcome submissions of original articles as well as reviews of any topics related to RNA modifications for a better understanding on new perspectives and interpretations as well as novel technological and theoretical progresses.

Dr. Kumiko UI-TEI
Guest Editor

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