Special Issue "Design and Application of Biomedical Circuits and Systems"

A special issue of Electronics (ISSN 2079-9292). This special issue belongs to the section "Bioelectronics".

Deadline for manuscript submissions: 31 December 2019.

Special Issue Editors

Prof. Dr. Alberto Yufera
E-Mail Website
Guest Editor
Universidad de Sevilla, Instituto de Microelectronica de Sevilla (US/IMSE), Spain.
Interests: biomedical circuit applications based on bioimpedance; bio-sensors and microelectrodes; analysis and design of analog integrated circuits and systems for signal processing; CAD tools for analog circuits
Prof. Dr. Gloria Huertas
E-Mail Website
Guest Editor
Universidad de Sevilla, Instituto de Microelectronica de Sevilla (US/IMSE), Spain.
Interests: biomedical circuits and systems, bio-sensors, laboratory on-a-chip (LoC), bioimpedance, microelectrode, design for test.
Prof. Dr. Belen Calvo
E-Mail Website
Guest Editor
Group of Electronic Design, Aragon Institute for Engineering Research (GDE-I3A), University of Zaragoza, Spain.
Interests: analog and mixed-mode CMOS IC design, low-voltage low-power monolithic sensor interfaces, smart instrumentation.

Special Issue Information

Dear Colleagues,

The development of new sensing technologies, biomaterials, microelectronic devices, microfluidic systems and micro-electro-mechanical systems (MEMs), etc., opens the window to new biomedical circuit and system opportunities to measure “better”, and also using “alternative” methods, to find relevant information for physician and biologist teams, with applications such as diagnosis, therapy, clinical testing and bio-signal monitoring. However, the accomplishment of new medical equipment for specific tests in the health field pose significant challenges in the electronic circuits and systems needed, whose performance is vital for proper and accurate data acquisition tasks.

This Special Issue is devoted mainly to incorporating proposals of bio-sensing signals based on new circuits and systems approaches. In general, it is focused on new bio-signal analog front-end (AFE) circuits; specific circuit development for known and new sensor/sensing approaches; circuits for biomedical signal processing; low-voltage and low-power circuits and their application to implantable and wearable devices; circuits and systems for clinical applications; circuits for sensing/actuation in MEM systems, Lab-on-a-Chip (LoC), micro-total-analysis Systems (uTAS); cell assays and manipulation, etc. The main topics of interest include, but are not limited to:

  • Analog front-end (AFE) circuits
  • Circuits for bioimpedance testing
  • Capacitive-based circuits
  • Circuits for new sensing devices and microelectrodes
  • ECG, EEG, EMG, EoG, etc., circuits and systems
  • Circuits for implantable and wearable devices
  • LP/LV circuits in biomedical environments
  • Micro-energy harvesting
  • Circuits and systems in clinical applications
  • Circuits for cell, DNA, bacteria, virus, etc., assays
  • Brain interfaces
  • Internet of things for remote healthcare

Prof. Dr. Alberto Yufera
Prof. Dr. Gloria Huertas
Prof. Dr. Belen Calvo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Electronics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Analog front-end (AFE) circuits
  • Bioimpedance
  • Microelectrodes and MEAs
  • Biosensors
  • Lab-on-a-Chip (LoC)
  • ECG, EEG, EMG, EoG, etc., circuits and systems
  • Circuits for implantable and wearable devices
  • LP/LV circuits in biomedical environments
  • Micro-energy harvesting
  • Circuits and systems in clinical applications
  • Circuits for cell, DNA, bacteria, virus, etc., assays
  • Brain interfaces
  • Internet of things for remote healthcare

Published Papers (4 papers)

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Research

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Open AccessArticle
A Computationally Efficient Mean Sound Speed Estimation Method Based on an Evaluation of Focusing Quality for Medical Ultrasound Imaging
Electronics 2019, 8(11), 1368; https://doi.org/10.3390/electronics8111368 - 18 Nov 2019
Abstract
Generally, ultrasound receive beamformers calculate the focusing time delays of fixed sound speeds in human tissue (e.g., 1540 m/s). However, phase distortions occur due to variations of sound speeds in soft tissues, resulting in degradation of image quality. Thus, an optimal estimation of [...] Read more.
Generally, ultrasound receive beamformers calculate the focusing time delays of fixed sound speeds in human tissue (e.g., 1540 m/s). However, phase distortions occur due to variations of sound speeds in soft tissues, resulting in degradation of image quality. Thus, an optimal estimation of sound speed is required in order to improve image quality. Implementation of real-time sound speed estimation is challenging due to high computational and hardware complexities. In this paper, an optimal sound speed estimation method with a low-cost hardware resource is presented. In the proposed method, the optimal mean sound speed is determined by measuring the amplitude variance of pre-beamformed radio-frequency (RF) data. The proposed method was evaluated with phantom and in vivo experiments, and implemented on Virtex-4 with Xilinx ISE 12.4 using VHDL. Experiment results indicate that the proposed method could estimate the mean optimal sound speed and enhance spatial resolution with a negligible increase in the hardware resource usage. Full article
(This article belongs to the Special Issue Design and Application of Biomedical Circuits and Systems)
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Open AccessFeature PaperArticle
Incremental Low Rank Noise Reduction for Robust Infrared Tracking of Body Temperature during Medical Imaging
Electronics 2019, 8(11), 1301; https://doi.org/10.3390/electronics8111301 - 07 Nov 2019
Abstract
Thermal imagery for monitoring of body temperature provides a powerful tool to decrease health risks (e.g., burning) for patients during medical imaging (e.g., magnetic resonance imaging). The presented approach discusses an experiment to simulate radiology conditions with infrared imaging along with an automatic [...] Read more.
Thermal imagery for monitoring of body temperature provides a powerful tool to decrease health risks (e.g., burning) for patients during medical imaging (e.g., magnetic resonance imaging). The presented approach discusses an experiment to simulate radiology conditions with infrared imaging along with an automatic thermal monitoring/tracking system. The thermal tracking system uses an incremental low-rank noise reduction applying incremental singular value decomposition (SVD) and applies color based clustering for initialization of the region of interest (ROI) boundary. Then a particle filter tracks the ROI(s) from the entire thermal stream (video sequence). The thermal database contains 15 subjects in two positions (i.e., sitting, and lying) in front of thermal camera. This dataset is created to verify the robustness of our method with respect to motion-artifacts and in presence of additive noise (2–20%—salt and pepper noise). The proposed approach was tested for the infrared images in the dataset and was able to successfully measure and track the ROI continuously (100% detecting and tracking the temperature of participants), and provided considerable robustness against noise (unchanged accuracy even in 20% additive noise), which shows promising performance. Full article
(This article belongs to the Special Issue Design and Application of Biomedical Circuits and Systems)
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Open AccessFeature PaperArticle
Soft Elbow Exoskeleton for Upper Limb Assistance Incorporating Dual Motor-Tendon Actuator
Electronics 2019, 8(10), 1184; https://doi.org/10.3390/electronics8101184 - 18 Oct 2019
Abstract
Loss of muscle functions, such as the elbow, can affect the quality of life of a person. This research is aimed at developing an affordable two DOF soft elbow exoskeleton incorporating a dual motor-tendon actuator. The soft elbow exoskeleton can be used to [...] Read more.
Loss of muscle functions, such as the elbow, can affect the quality of life of a person. This research is aimed at developing an affordable two DOF soft elbow exoskeleton incorporating a dual motor-tendon actuator. The soft elbow exoskeleton can be used to assist two DOF motions of the upper limb, especially elbow and wrist movements. The exoskeleton is developed using fabric for the convenience purpose of the user. The dual motor-tendon actuator subsystem employs two DC motors coupled with lead-to-screw converting motion from angular into linear motion. The output is connected to the upper arm hook on the soft exoskeleton elbow. With this mechanism, the proposed actuator system is able to assist two DOF movements for flexion/extension and pronation/supination motion. Proportional-Integral (PI) control is implemented for controlling the motion. The optimized value of Kp and Ki are 200 and 20, respectively. Based on the test results, there is a slight steady-state error between the first and the second DC motor. When the exoskeleton is worn by a user, it gives more steady-state errors because of the load from the arm weight. The test results demonstrate that the proposed soft exoskeleton elbow can be worn easily and comfortably by a user to assist two DOF for elbow and wrist motion. The resulted range of motion (ROM) for elbow flexion–extension can be varied from 90° to 157°, whereas the maximum of ROM that can be achieved for pronation and supination movements are 19° and 18°, respectively. Full article
(This article belongs to the Special Issue Design and Application of Biomedical Circuits and Systems)
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Review

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Open AccessFeature PaperReview
Insight on Electronic Travel Aids for Visually Impaired People: A Review on the Electromagnetic Technology
Electronics 2019, 8(11), 1281; https://doi.org/10.3390/electronics8111281 - 04 Nov 2019
Abstract
This review deals with a comprehensive description of the available electromagnetic travel aids for visually impaired and blind people. This challenging task is considered as an outstanding research area due to the rapid growth in the number of people with visual impairments. For [...] Read more.
This review deals with a comprehensive description of the available electromagnetic travel aids for visually impaired and blind people. This challenging task is considered as an outstanding research area due to the rapid growth in the number of people with visual impairments. For decades, different technologies have been employed for solving the crucial challenge of improving the mobility of visually impaired people, but a suitable solution has not yet been developed. Focusing this contribution on the electromagnetic technology, the state-of-the-art of available solutions is demonstrated. Electronic travel aids based on electromagnetic technology have been identified as an emerging technology due to their high level of achievable performance in terms of accuracy, flexibility, lightness, and cost-effectiveness. Full article
(This article belongs to the Special Issue Design and Application of Biomedical Circuits and Systems)
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