Special Issue "Use of Molecular Markers in Genetic Diversity Research"
A special issue of Diversity (ISSN 1424-2818).
Deadline for manuscript submissions: closed (31 January 2014)
Prof. Dr. Mario A. Pagnotta
Dipartimento di Scienze Agrarie e Forestali (DAFNE), Department of Agricultural and Forestry scieNcEs, Tuscia University, Via S. C. de Lellis, snc 01100 Viterbo, Italy
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Interests: plant population genetics; plant evolution and domestication; in situ and ex situ conservation of plant germplasm; molecular characterization; molecular markers; molecular evolution; plant breeding
A molecular marker can be defined as a genomic locus, detected through probe or specific starters (primer) which, in virtue of its presence, distinguishes unequivocally the chromosomic trait which it represents as well as the flanking regions at the 3’ and 5’ extremity. Thus, these markers, generally have no reference to the activity of specific genes, but are directly based on highlighting differences (polymorphisms) within a nucleic sequence in different individuals, as a result of insertion, deletions, translocations, duplications, point mutations, etc. Molecular marker is probably the more powerful tool developed at the end of last century. Thousands of them are now known, thus enabling the study of a much larger number of genes that code for plant expression, as well as for other non-coding segments of the chromosome. Thanks to them genetic maps have been developed and their position in the genome is known. They are widely used in several aspects from variety identification, to gene detection passing from the assessing of genetic diversity and its partition within and among populations. More and more, molecular marker studies are being used to identify diversity “hotspots” for in situ conservation.
Several molecular markers typologies are developed and each typology has its own property with advantages and disadvantages.
The aim of this special issues is to bring together researches addressed to assess by molecular markers the genetic diversity present in the germplasm. But also addressed to evaluate and develop the most suitable marker(s) to be use as well as the statistical analysis which their use imply.
Prof. Dr. Mario A. Pagnotta
Manuscript Submission Information
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- genetic diversity
- markers developing
- population genetics
- molecular evolution
- molecular marker
- statistical analysis