Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnosis and Management of Multisystem Wilson’s Disease submission deadline 31 Oct 2026 | 1 articles | Viewed by 1564 | Submission Open
Keywords: Wilson’s disease; brain magnetic resonance imaging; biomarkers; copper metabolism; Wilson’s disease mimicking disorders; zinc; chelators; liver transplantation
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnosis and Prognosis in Otorhinolaryngology and Head and Neck Surgery submission deadline 31 Oct 2026 | 1 articles | Viewed by 1487 | Submission Open
Keywords: otorhinolaryngologic neoplasms; head and neck neoplasms; diagnostic techniques and procedures; prognosis; biomarkers, tumor; precision medicine; artificial intelligence; radiomics; molecular diagnostic techniques; disease progression
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Focus on Children's Oral Health: Advances in Pediatric Dentistry and Imaging Assessments
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1455 | Submission Open
Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics; imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Clinical Advances in Fetal Medicine: Diagnosis and Management submission deadline 31 Oct 2026 | Viewed by 1343 | Submission Open
Keywords: prenatal diagnosis; fetal therapy; congenital anomalies; imaging; molecular diagnostics; fetal intervention; ethics; precision fetal medicine; congenital diaphragmatic hernia; spina bifida; gastroschisis; sacro-coccygeal teratoma; vein of galen; twin–twin transfusion syndrome; congenital cardiac malformation; congenital pulmonary airway malformation; lower urinary tract obstruction
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Molecular Pathology in Maternal–Fetal Medicine: Enabling Precision Diagnosis and Prenatal Management
edited by , Songchang Chen and Yousheng Yan
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1271 | Submission Open
Keywords: molecular pathology; prenatal screening; prenatal diagnosis; pregnancy complications; bioinformatics; clinical artificial intelligence
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Musculoskeletal Radiology
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1264 | Submission Open
Keywords: musculoskeletal radiology; high-resolution MRI; ultrasound-guided interventions; artificial intelligence in imaging; CT imaging techniques
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnosis and Management of Endocrine Disorders submission deadline 31 Oct 2026 | 1 articles | Viewed by 1189 | Submission Open
Keywords: type 2 diabetes; growth hormone deficiency; dyslipidemia; osteoporosis; hyperprolactinemia; hyperthyroidism
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 3rd Edition submission deadline 31 Oct 2026 | 1 articles | Viewed by 1095 | Submission Open
Keywords: machine learning; neurodegenerative diseases; diagnosis; detection and evaluation; monitoring
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Diagnosis and Prognosis of Heart Disease, 3rd Edition
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 969 | Submission Open
Keywords: heart disease; coronary artery disease; arrhythmia; heart failure; diagnosis; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in Gynecological and Pediatric Imaging
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 878 | Submission Open
Keywords: gynecological imaging; pediatric imaging; obstetrics imaging; magnetic resonance imaging (MRI); computed tomography (CT); ultrasound; early detection; congenital anomalies
(This special issue belongs to the Section Medical Imaging and Theranostics)
Innovations and Challenges in Breast Imaging
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 852 | Submission Open
Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures; artificial intelligence in imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
AI-Driven Bioinformatics for Precision and Next-Generation Diagnostics
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 667 | Submission Open
Keywords: artificial intelligence (AI); machine learning; bioinformatics; next-generation diagnostics; high-throughput omics technologies; digital health platforms; biomarker discovery; digital pathology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Clinical Predictors of Endodontic Treatment Outcomes submission deadline 31 Oct 2026 | Viewed by 594 | Submission Open
Keywords: diagnosis; endodontics; radiographic imaging; CBCT; outcomes; histology; preoperative diagnosis; apical periodontitis status; clinical predictors treatment planning, improve patient communication, and guide evidence-based decision-making
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Imaging in Acute Respiratory Distress Syndrome
edited by
submission deadline 31 Oct 2026 | Viewed by 569 | Submission Open
Keywords: acute respiratory distress syndrome (ARDS); computed tomography (CT); lung ultrasound (LUS); electrical impedance tomography (EIT); positron emission tomography (PET); imaging biomarkers; quantitative imaging analysis; multimodal imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Wearable Devices for Health Monitoring and Disease Diagnosis
edited by Robert LeMoyne
submission deadline 31 Oct 2026 | Viewed by 515 | Submission Open
Keywords: wearable devices; health monitoring; diagnosis; sensors; artificial intelligence
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Functional Parameters in Quantitative CT: Clinical Significance and Diagnostic Applications
edited by Massimo Cressoni and Fatemeh Darvizeh
submission deadline 31 Oct 2026 | Viewed by 494 | Submission Open
Keywords: computed tomography; dual energy; adrenal adenoma; cardiac function; kidney function; perfusion; contrast media; flow velocity; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Laboratory Hematology and Flow Cytometry
edited by and Cara Lunn Shirai
submission deadline 31 Oct 2026 | 1 articles | Viewed by 485 | Submission Open
Keywords: flow cytometry; spectral flow cytometry; imaging flow cytometry; machine learning in flow cytometry; artificial intelligence in flow cytometry; machine learning in laboratory hematology; artificial intelligence in laboratory hematology; hematology laboratory information systems; automated hematology; complete blood count; hemoglobin analysis
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer
edited by Nicola Normanno, and
submission deadline 31 Oct 2026 | Viewed by 455 | Submission Open
Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence
Deep Learning-Based Medical Diagnostics
edited by
submission deadline 31 Oct 2026 | Viewed by 396 | Submission Open
Keywords: deep learning in medical diagnostics; multimodal diagnostic data fusion; AI-assisted medical imaging; biomedical signal analysis; computer-assisted diagnosis; explainable artificial intelligence in healthcare; wearable and point-of-care diagnostics; clinical validation of AI models; intelligent medical decision support
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Laboratory Testing in Endocrine Diseases
edited by and Chin Shern Lau
submission deadline 31 Oct 2026 | Viewed by 389 | Submission Open
Keywords: endocrine diseases; laboratory testing; clinical correlation; hormone testing; diagnosis and management
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advancements in Cardiovascular Imaging
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 346 | Submission Open
Keywords: coronary CTA; coronary artery disease; computed tomography angiography; spectral imaging; photon-counting CT; atherosclerosis; structural heart disease; valves and devices; atrial fibrillation; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Biological Rhythms in Laboratory Medicine submission deadline 31 Oct 2026 | Viewed by 293 | Submission Open
Keywords: biological rhythms; laboratory medicine; biomarkers; physiology
(This special issue belongs to the Section Clinical Laboratory Medicine)
The Use of Portable Devices in Emergency Medicine, Second Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 292 | Submission Open
Keywords: portable devices; emergency medicine; smartphone applications; wearable technology; diagnostic accuracy; remote triage; real-time monitoring; emergency medicine education; point-of-care testing; telemedicine
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Diagnosis and Management of Esophageal Disorders: Modern Approaches
edited by and John Jacobs
submission deadline 31 Oct 2026 | Viewed by 281 | Submission Open
Keywords: eosinophilic esophagitis; GERD; achalasia; esophagogastric junction outflow obstruction; lichen planus
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Inflammatory and Infectious Skin Diseases: From Diagnostics to Management submission deadline 31 Oct 2026 | Viewed by 274 | Submission Open
Keywords: skin infections; sexually transmitted infections; human papillomavirus; syphilis; pityriasis rosea; exanthem
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Recent Advances in Endoscopy and Robotic Surgery submission deadline 31 Oct 2026 | Viewed by 272 | Submission Open
Keywords: endoscopy; medical imaging; medical image analysis; computer-aided diagnosis; clinical validation; cancer detection; inflammatory disease; robotic surgery; endoscopic surgery; surgical data science
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in the Diagnosis and Management of Vasculitis—2nd Edition submission deadline 31 Oct 2026 | Viewed by 268 | Submission Open
Keywords: vasculitis; advances; updates; management; treatment; therapy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Novel Technologies in Orthopedic Surgery: Diagnosis and Management, 2nd Edition
edited by Giuseppe Salvatore and Alessandro Mazzola
submission deadline 31 Oct 2026 | Viewed by 261 | Submission Open
Keywords: orthopedic surgery; orthopedic diagnosis; orthopedics; computer navigation and augmented reality; robotics; digital templating; 3D printing; artificial intelligence; machine learning; deep learning
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Liquid Chromatography–Mass Spectrometry (LC-MS) in the Clinical Laboratory, 2nd Edition submission deadline 31 Oct 2026 | Viewed by 251 | Submission Open
Keywords: LC-MS; clinical diagnostics; biomarker discovery; metabolomics; lipidomics; clinical samples; method validation; precision medicine; analytical techniques
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in Molecular Residual Disease: From Biomarkers to Precision Medicine
edited by and Sarabjot Pabla
submission deadline 31 Oct 2026 | Viewed by 245 | Submission Open
Keywords: molecular residual disease (MRD); liquid biopsy; next-generation sequencing (NGS); ultrasensitive sequencing; multi-modal biomarkers; artificial intelligence; radiomics; circulating tumor DNA (ctDNA); clinical trial endpoint; precision oncology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Next Laboratory Tumor Diagnostics Using Immunologic Methods
edited by and Sookwon Ryu
submission deadline 31 Oct 2026 | Viewed by 235 | Submission Open
Keywords: tumor marker; immunotherapy; laboratory medicine; diagnostic immunology; immunologic biosensors
(This special issue belongs to the Section Clinical Laboratory Medicine)
Diagnosis and Management of Ear Diseases
edited by
submission deadline 31 Oct 2026 | Viewed by 163 | Submission Open
Keywords: ear diseases; hearing loss; otitis media; cholesteatoma; vestibular disorders; endoscopic ear surgery; diagnostic imaging; artificial intelligence; digital health; clinical outcomes
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnosis, Management, and Prognosis of Liver Diseases
edited by
submission deadline 31 Oct 2026 | Viewed by 162 | Submission Open
Keywords: acute liver disease; chronic liver disease; viral hepatitis; liver cirrhosis; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); hepatocellular carcinoma; biomarkers; artificial intelligence; precision medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Clinical Diagnosis and Prognosis of Urologic Oncology
edited by
submission deadline 31 Oct 2026 | Viewed by 145 | Submission Open
Keywords: biomarkers; molecular diagnostics; precision medicine; urologic oncology; clinical prognosis; disease stratification
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Precision Screening and Risk-Based Management in Women’s Health
edited by
submission deadline 31 Oct 2026 | Viewed by 140 | Submission Open
Keywords: precision screening; risk-based management; women’s health; gynecologic cancer; cervical cancer screening; HPV testing; cervical neoplasia; endometrial cancer; ovarian cancer; biomarkers; molecular diagnostics; risk stratification; cytology; epidemiology; precision prevention
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Advances in Obstetrics and Gynecology, Breast Disease and Women’s Health
edited by Menelaos Zafrakas
submission deadline 30 Nov 2026 | 6 articles | Viewed by 32805 | Submission Open
Keywords: obstetrics; gynecology; maternal–fetal medicine; breast; women’s health; diagnostics
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advancing Clinical Diagnosis with Artificial Intelligence: Applications, Challenges, and Future Directions
edited by , , Shonak Bansal and
submission deadline 30 Nov 2026 | 9 articles | Viewed by 19318 | Submission Open
Keywords: deep learning; artificial intelligence (AI); internet of medical things (IoMT); AI-assisted diagnostics; multimodal clinical data; data-driven healthcare
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Diagnostics of Chronic Kidney Disease submission deadline 30 Nov 2026 | 5 articles | Viewed by 12247 | Submission Open
Keywords: chronic kidney disease; diabetic nephropathy; glomerulonephritis; acid–base disorders; uremic toxin; artificial intelligence; metabolic bone disease; vascular access; arteriovenous fistula; catheter; hemodialysis
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Application of Artificial Intelligence to Advance Individualized Diagnosis and Treatment in Emergency and Critical Care Medicine, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 6 articles | Viewed by 11637 | Submission Open
Keywords: critical care; sepsis; artificial intelligence; predictive analytics; clustering; acute kidney injury; emergency medicine; transcriptome
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Diagnosis, Treatment, and Prognosis of Breast Cancer
edited by
submission deadline 30 Nov 2026 | 7 articles | Viewed by 9765 | Submission Open
Keywords: breast cancer diagnosis; molecular profiling; artificial intelligence; targeted therapy; immunotherapy; treatment strategies; prognostic markers; triple-negative breast cancer
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition
edited by Costantino Ricci
submission deadline 30 Nov 2026 | 5 articles | Viewed by 9499 | Submission Open
Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Alzheimer's Disease Diagnosis Based on Deep Learning
edited by Anees Abrol
submission deadline 30 Nov 2026 | 4 articles | Viewed by 8134 | Submission Open
Keywords: Alzheimer's disease (AD); deep learning; MRI; demographic information; disease probability map; convolutional neural network (CNN)
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Point-of-Care Testing (POCT) for Infectious Diseases
edited by Rongzhang Hao
submission deadline 30 Nov 2026 | 6 articles | Viewed by 7962 | Submission Open
Keywords: point-of-care testing (POCT); microfluidic chip and biosensor; ultrafast detection techniques; AI-integrated testing systems; infectious disease; pathogen
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition submission deadline 30 Nov 2026 | 2 articles | Viewed by 7838 | Submission Open
Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Opportunities in Laboratory Medicine in the Era of Genetic Testing
edited by
submission deadline 30 Nov 2026 | 5 articles | Viewed by 6325 | Submission Open
Keywords: laboratory medicine; genetic testing; molecular diagnostics; personalized medicine; clinical decision-making; infectious disease diagnosis; precision oncology
(This special issue belongs to the Section Clinical Laboratory Medicine)
Diagnosis and Management of Vascular Diseases
edited by Tiffany R. Bellomo and Abhisekh A. Mohapatra
submission deadline 30 Nov 2026 | 4 articles | Viewed by 5272 | Submission Open
Keywords: diagnosis; management; vascular diseases; marker; non-invasive imaging
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnosis and Management of Dental Medicine and Surgery, 2nd Edition submission deadline 30 Nov 2026 | 4 articles | Viewed by 5052 | Submission Open
Keywords: oral surgery; oral medicine; implant dentistry; gerontology; bone regeneration; oral rehabilitation
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence in Medical Imaging: Innovations and Diagnostic Applications
edited by , Moumen Elmelegy, and
submission deadline 30 Nov 2026 | 4 articles | Viewed by 4691 | Submission Open
Keywords: medical imaging; artificial intelligence; disease diagnosis; radiomics
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI for Medical Diagnosis: From Algorithms to Clinical Integration
edited by
submission deadline 30 Nov 2026 | 6 articles | Viewed by 4031 | Submission Open
Keywords: novel neural architectures; explainable and trustworthy AI (XAI); medical foundation models; algorithmic robustness and generalization; multimodal data integration; data-efficient learning (few-shot/self-supervised); clinical decision support systems (CDSSs); real-time diagnostic algorithms; edge AI for medical devices
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Magnetic Resonance Imaging
edited by
submission deadline 30 Nov 2026 | 3 articles | Viewed by 3825 | Submission Open
Keywords: magnetic resonance imaging; artificial intelligence; diagnostic medicine; MRI data analysis; image processing
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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