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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Diagnosis and Management in Anesthesia and Pain Medicine: 2nd Edition

edited by Jamal Hasoon

submission deadline 28 Feb 2027 | Viewed by 473 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Prognostic Evaluation of Urological Diseases

edited by

Uroš Bumbaširević

submission deadline 28 Feb 2027 | Viewed by 459 | Submission Open

Keywords: urological diseases; diagnosis; prognosis; biomarkers; prostate diseases; benign prostatic hyperplasia; bladder cancer; testicular cancer; urolithiasis; endourology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Computational and Functional Diagnostic Approaches in Behavioral and Clinical Neurosciences

edited by

Marco Esposito

Marcella Caputi

Roberta Fadda

and Antonio Cerasa

submission deadline 28 Feb 2027 | Viewed by 420 | Submission Open

Keywords: computational diagnostics; behavioral assessment; multimodal biomarkers; nutritional and metabolic indicators; physiological; neuroimaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Diagnostic Technologies in Orthopedics: Advancing Personalized Implant Design and Therapeutics

edited by

Neil Ashwood

submission deadline 28 Feb 2027 | Viewed by 343 | Submission Open

Keywords: patient-specific implant design; advanced diagnostic technologies; computational biomechanics; surgical navigation systems; implant manufacturing; intraoperative monitoring; postoperative evaluation; biomedical engineering; clinical implant optimization; precision medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Updates in Neuropathology

edited by

Gianluca Marucci

submission deadline 28 Feb 2027 | Viewed by 306 | Submission Open

Keywords: brain tumors; epilepsy surgery; neurovascular diseases; peripheral neuropathy; glioblastoma; CNS metastases; methylation profiling; neuro-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Treatment of Digestive System Diseases

edited by

Zhendong Jin

submission deadline 28 Feb 2027 | Viewed by 295 | Submission Open

Keywords: digestive system diseases; endoscopic diagnostic techniques; AI-assisted endoscopy; gastrointestinal malignancy; molecular biomarkers; minimally invasive therapy; precision diagnosis; clinical translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Challenges in Complex and Severe Allergic Conditions

edited by Yuxiang Zhi

submission deadline 28 Feb 2027 | Viewed by 259 | Submission Open

Keywords: diagnostic challenges; severe allergic condition; biomarkers; immunologic testing; cellular mechanisms

Recent Developments in the Diagnosis of Gastrointestinal Diseases

edited by

Nikhitha Mantri

and Sridhar S. Chilimuri

submission deadline 28 Feb 2027 | Viewed by 189 | Submission Open

Keywords: endoscopy; biomarkers; non-invasive testing; screening; artificial intelligence; cancer; early detection

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Tropical Diseases: Recent Advances in Epidemiology, Diagnosis and Management

edited by

Luiz Euribel Prestes Carneiro

submission deadline 28 Feb 2027 | Viewed by 184 | Submission Open

Keywords: tropical diseases; neglected tropical diseases; epidemiology; diagnosis; vector-borne diseases; one health; emerging infectious diseases; global health

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Brain Injury: Diagnostic and Prognostic Insights

edited by Pál Barzó

submission deadline 28 Feb 2027 | Viewed by 57 | Submission Open

Keywords: traumatic brain injury; TBI; diffuse axonal injury; DAI; diffusion tensor imaging; DTI; probabilistic tractography; functional outcome; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Digital Innovations in Obstetrics and Gynecology: Artificial Intelligence, Diagnostic Advances, and Clinical Decision-Making

edited by

Iason Psilopatis

submission deadline 20 Mar 2027 | Viewed by 975 | Submission Open

Keywords: obstetrics; gynecology; artificial intelligence; diagnostic imaging; digital diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition

edited by

Jesús Ramírez-Bermúdez

submission deadline 31 Mar 2027 | 6 articles | Viewed by 27425 | Submission Open

Keywords: neuropsychiatric disorders; autism; mania; depression; imaging; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Utilization of Liquid Biopsy in Cancer Diagnosis and Management 2025–2026

edited by

Consolato M. Sergi

submission deadline 31 Mar 2027 | 5 articles | Viewed by 16068 | Submission Open

Keywords: liquid biopsy; precision medicine; cancer diagnostics; nanotechnologies; markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Detection and Characterization of Focal Lesions in the Solid Abdominal Organs

edited by

Gavin Low

submission deadline 31 Mar 2027 | 4 articles | Viewed by 9167 | Submission Open

Keywords: diagnostic imaging ; disease diagnosis; detection or characterization ; multi-modality imaging ; morphologic and functional assessments

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis of Nervous System Diseases—3rd Edition

edited by

Vasileios T. Papaliagkas

submission deadline 31 Mar 2027 | 6 articles | Viewed by 8532 | Submission Open

Keywords: neuroimaging; neurodegenerative diseases; Alzheimer's disease; cognitive impairment; brain tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy

edited by

Caterina Carollo

submission deadline 31 Mar 2027 | 4 articles | Viewed by 8218 | Submission Open

Keywords: kidney; nephrology; ultrasounds; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Abdominal Ultrasound: A Left Behind Area—2nd Edition

edited by Hiroko Naganuma

submission deadline 31 Mar 2027 | 4 articles | Viewed by 8149 | Submission Open

Keywords: liver tumor; drainage vessel; precursor lesion; gallbladder cancer; peritoneum; mesentery; ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

PET/CT Imaging in Oncology: Clinical Advances and Perspectives

edited by

Francesco Lanfranchi

submission deadline 31 Mar 2027 | 4 articles | Viewed by 7735 | Submission Open

Keywords: PET/CT imaging; molecular imaging; oncology; cancer diagnosis; precision oncology; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Advances and Applications in Neuroradiology: 2nd Edition

edited by

Houman Sotoudeh

submission deadline 31 Mar 2027 | 4 articles | Viewed by 6111 | Submission Open

Keywords: neuroradiology; advanced imaging; susceptibility-weighted imaging (SWI); diffusion tensor imaging (DTI); functional MRI (fMRI); CT perfusion; MR perfusion; MR spectroscopy; PET; molecular imaging; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Diagnostic and Interventional Cardiology: Bridging Imaging, Physiology, and Therapy

edited by Samit Shah and

Natalija Odanovic

submission deadline 31 Mar 2027 | 5 articles | Viewed by 5940 | Submission Open

Keywords: EKG; CCTA; MRI; SPECT; PET; Echo; OCT; IVUS; QFR; angioIMR

(This special issue belongs to the Section Medical Imaging and Theranostics)

Histopathology in Cancer Diagnosis and Prognosis—2nd Edition

edited by

Christina Magkou

submission deadline 31 Mar 2027 | 1 articles | Viewed by 5704 | Submission Open

Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Imaging of Pulmonary Diseases

edited by

Marcel Koenigkam Santos

submission deadline 31 Mar 2027 | 5 articles | Viewed by 5565 | Submission Open

Keywords: diagnosis; imaging; pulmonology; thoracic surgery; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathogenesis and Early Diagnosis of HPV-Related Cancers and Pre-Cancers

edited by

Anna Daniela Iacobone

and

Marta Tagliabue

submission deadline 31 Mar 2027 | 4 articles | Viewed by 5503 | Submission Open

Keywords: HPV-related cancer; molecular diagnostics; precancerous lesions; biomarkers; early detection; cervical cancer; anal cancer; oropharyngeal cancer; prognostic factors; HPV genotyping

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Photon-Counting CT in Clinical Application

edited by Philipp Gruschwitz

submission deadline 31 Mar 2027 | 4 articles | Viewed by 4651 | Submission Open

Keywords: protocol development and optimization; spectral imaging; tissue characterization; lesion classification; benefits of special resolution; radiation dose optimization; contrast agent

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Gynecological Disorders

edited by

Yasushi Kotani

submission deadline 31 Mar 2027 | 3 articles | Viewed by 4425 | Submission Open

Keywords: gynecological diseases; diagnosis; management strategies; obstetrics and gynecology; women’s health; clinical practice guidelines; reproductive health disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Radiology for Breast Cancer

edited by Romuald Ferré

submission deadline 31 Mar 2027 | 6 articles | Viewed by 4370 | Submission Open

Keywords: breast cancer screening; digital breast tomosynthesis (DBT); contrast-enhanced mammography (CEM); abbreviated breast MRI; artificial intelligence and radiomics; ultrasound correlation; risk-stratified imaging pathways

(This special issue belongs to the Section Medical Imaging and Theranostics)

Neurofibromatosis and Schwannomatosis: Diagnosis and Management

edited by Walter Taal and Enrico Martin

submission deadline 31 Mar 2027 | 3 articles | Viewed by 4222 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); neurofibromatosis type 2 (NF2); schwannomatosis (SWN); neurofibromas; schwannomas; malignant peripheral nerve sheath tumor (MPNST); glioma; tumor management; genetic counseling; quality of life (QoL)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Medical Image Processing

edited by Zhiwei Wang

submission deadline 31 Mar 2027 | 7 articles | Viewed by 4181 | Submission Open

Keywords: medical image processing; foundation models; multimodal learning; computer-aided diagnosis; image segmentation and registration; generative AI; clinical decision support; representation learning; explainable and trustworthy AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Advances in Dentomaxillofacial Radiology

edited by

Paulo Sérgio da Silva Santos

submission deadline 31 Mar 2027 | Viewed by 3918 | Submission Open

Keywords: cone-beam computed tomography; diagnostic imaging; ultrasonography; mouth; diagnosis; oral

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic Options and Treatment Strategies for Neurological Disorders

edited by

Julia Koehn

and Jenny Stritzelberger

submission deadline 31 Mar 2027 | 5 articles | Viewed by 3623 | Submission Open

Keywords: neuroscience; diagnostic tools; point-of-care testing; prehospital care; emergency medicine; rapid and accurate diagnosis; treatment strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Mobility Medicine Diagnostics

edited by

Ugo Carraro

submission deadline 31 Mar 2027 | 1 articles | Viewed by 3515 | Submission Open

Keywords: mobility medicine; genetic and acquired neuromuscular disorders; mobility medicine of aging; mobility functional tests; skeletal muscle and cartilage imaging; quantitative tissue densitometry by 3D and 2D color CT and MRI; blood and mouth fluid biomarkers in mobility medicine; management and follow-up in mobility medicine; functional electrical stimulation of permanently denervated and reinnervating muscles

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI and Advanced Imaging in Oral and Maxillofacial Diagnostics

edited by

Gürkan Ünsal

and

Kaan Orhan

submission deadline 31 Mar 2027 | 1 articles | Viewed by 3443 | Submission Open

Keywords: artificial intelligence; deep learning; oral and maxillofacial radiology; cone-beam computed tomography (CBCT); computer-aided diagnosis; radiomics; dental imaging; AI-enhanced treatment planning; large language model applications in radiology; automated pathology detection

(This special issue belongs to the Section Medical Imaging and Theranostics)

Ultrasound in the Diagnosis and Management of Skin Diseases—2nd Edition

edited by

Joanna Czajkowska

Norbert Kiss

and Miklós Gyöngy

submission deadline 31 Mar 2027 | 1 articles | Viewed by 3164 | Submission Open

Keywords: skin diseases; ultrasound; skin cancer; machine learning; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk Factors for Frailty in Older Adults: Second Edition

edited by

Agustín Aibar Almazán

and

María del Carmen Carcelén-Fraile

submission deadline 31 Mar 2027 | 2 articles | Viewed by 2948 | Submission Open

Keywords: frailty; older adults; risk factors; mental health; physical function; cognition; multidimensional intervention; frailty screening; quality of life; sleep quality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Microbial Infections and Critical Care Medicine: Diagnosis and Management, 2nd Edition

edited by Eleni K. Mouloudi,

Serafeim Chrysovalantis Kotoulas

and Eleni Massa

submission deadline 31 Mar 2027 | 1 articles | Viewed by 2732 | Submission Open

Keywords: microbial infections; superbugs; antimicrobial resistance; multi-drug resistance; critical care; diagnosis; management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Innovations in Colorectal Cancer Detection and Diagnosis

edited by

Wei Xin

submission deadline 31 Mar 2027 | 3 articles | Viewed by 2222 | Submission Open

Keywords: colorectal cancer; early detection; diagnostic pathology; molecular biomarkers; microsatellite instability; next-generation sequencing; liquid biopsy; digital pathology; artificial intelligence; precision oncology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in the Diagnosis and Management of Sports Injuries

edited by

Alberto Grassi

submission deadline 31 Mar 2027 | 2 articles | Viewed by 2118 | Submission Open

Keywords: sport injuries; sport traumatology; arthroscopy; surgery; joints

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Obstetric Ultrasound

edited by

Florian Recker

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1922 | Submission Open

Keywords: obstetric ultrasound; prenatal diagnosis; fetal imaging; 3D/4D ultrasound; doppler ultrasound; artificial intelligence; ultrasound education; maternal–fetal medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Cardiology: 2nd Edition

edited by

Oskars Kalejs

submission deadline 31 Mar 2027 | 2 articles | Viewed by 1885 | Submission Open

Keywords: cardiology; heart disease; arrhythmia; myocardial infarction; angina pectoris; coronary artery disease; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Coherence Tomography in Ophthalmology: Advanced Diagnostics and Intraoperative Applications

edited by

Xiaogang Wang

submission deadline 31 Mar 2027 | 3 articles | Viewed by 1729 | Submission Open

Keywords: optical coherence tomography; retinal diseases; glaucoma; intraoperative imaging; surgical guidance; diagnostic imaging; vascular imaging; anterior segment; microvasculature; blood flow

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Advances in Cardiovascular Imaging

edited by

Misagh Piran

and

Negin Moghadasi

submission deadline 31 Mar 2027 | Viewed by 1611 | Submission Open

Keywords: cardiovascular imaging; artificial intelligence; multimodality imaging; structural heart disease; early diagnosis; risk stratification; clinical decision-making

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Acute Pancreatitis

edited by Farid Froghi and Mikael Hans Sodergren

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1493 | Submission Open

Keywords: acute pancreatitis; risk stratification; advanced imaging; biomarkers; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Applications of Electrodiagnosis in Neuromuscular Diseases

edited by

Donggyu Lee

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1132 | Submission Open

Keywords: electrodiagnosis; neuromuscular diseases; EMG (electromyography); nerve conduction studies; electrical stimulation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Implementation and Health System Advances in Point-of-Care Diagnostics in Low- and Middle-Income Countries

edited by Desmond Kuupiel

submission deadline 31 Mar 2027 | Viewed by 1122 | Submission Open

Keywords: point-of-care diagnostics; POC; point-of-care technologies; global health; diagnostics

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnostic Markers of Genitourinary Tumors: 2nd Edition

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1006 | Submission Open

Keywords: genitourinary tumors; diagnostic markers; biomarkers; molecular diagnostics; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Imaging and Radiotherapy for Hepato-Biliary and Pancreatic Tumors

edited by

Michele Fiore

, Gian Marco Petrianni and Gabriele D'Ercole

submission deadline 31 Mar 2027 | 1 articles | Viewed by 955 | Submission Open

Keywords: hepato-biliary tumors; pancreatic tumors; diagnostic imaging; radiotherapy; SBRT; IGRT; adaptive radiotherapy; imaging biomarkers; multimodal therapy; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Technological Breakthrough in Ophthalmology: Remember the Past, Cherish the Present, Research for the Future

edited by Andrei Theodor Bǎlǎşoiu

submission deadline 31 Mar 2027 | 1 articles | Viewed by 887 | Submission Open

Keywords: OCT/OCT-A; glaucoma; cataract; retinal diseases; ocular/adnexal oncology; cornea

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Diagnostics for Women’s Health

edited by

Dah Ching Ding

submission deadline 31 Mar 2027 | 1 articles | Viewed by 839 | Submission Open

Keywords: women’s health diagnostics; artificial intelligence; biomarkers; precision medicine; gynecology; obstetrics; imaging; digital health; molecular diagnostics; wearable technology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Musculoskeletal Ultrasound: Advances and Diagnostic Possibilities

edited by Jean Louis Brasseur

submission deadline 31 Mar 2027 | Viewed by 813 | Submission Open

Keywords: ultrasound; musculoskeletal ultrasound; muscle; musculoskeletal disorders; locomotor system

(This special issue belongs to the Section Medical Imaging and Theranostics)

Epilepsy: Challenges and Novel Strategies in Diagnostics and Management

edited by