Tumor Markers in Urological Cancers: Current Advances and Future Perspectives

Dear Colleagues,

Since its introduction in the late 1980s, the widespread use of PSA had led to overdiagnosis and to an increase in unnecessary biopsies, which has ultimately lead to overtreatment of low-risk prostate cancer. For bladder cancer and renal cell carcinoma, there are no specific diagnostic, prognostic, or predictive biomarkers. Testis cancer is generally silenced at an early stage, leading to loss of the opportunity for early diagnosis and treatment. Notably, the identification of noninvasive biomarkers will provide useful tools for personalized medicine. Unfortunately, currently used biomarkers for urological cancers are far from ideal, lacking specificity and sensitivity. Many candidate molecules that act as potential biomarkers for clinical management of patients with prostate, bladder, testis, and renal cancers have been proposed.

Thus, the content of the Special Issue will focus on general approaches that will contribute to identifying noninvasive biomarkers useful for diagnosis, prognosis, and follow-up of patients with urological cancers.
Original research articles and full reviews are welcome.

On behalf of the Diagnostics, you are warmly invited to contribute an article to the Special Issue “Tumor Markers in Urological Cancers: Current Advances and Future Perspectives.

Prof. Daniela Terracciano
Guest Editor

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