Next-Generation Sequencing in Tumor Diagnosis and Treatment II
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 March 2022) | Viewed by 25081
Special Issue Editors
Interests: next-generation sequencing; predictive markers in solid tumors; molecular pathology
Special Issues, Collections and Topics in MDPI journals
Interests: predictive molecular pathology in solid tumors; next generation technologies in molecular biology; liquid biopsies; predictive oncology
Special Issues, Collections and Topics in MDPI journals
Interests: gastrointestinal pathology; molecular pathology; preinvasive lesions; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Next-generation sequencing (NGS) allows for the sequencing of multiple genes at a very high depth of coverage. The principle of targeted therapy consists in the application of drugs targeted against well-defined molecules that play a key role in tumor progression and/or survival. Considering the continuous discovery of new molecules as a putative target or that are responsible for treatment resistance mechanisms, single-gene diagnostics is becoming less effective. At present, precision medicine requires multigene characterization. The introduction of NGS to molecular diagnostics has allowed us to combine high analytical sensitivity with multigene analysis. The aim of this Special Issue is to focus on the application of NGS in characterizing molecular alterations in solid tumors for diagnostic, prognostic, or predictive purposes. We invite researchers and authors to submit original research on the application of NGS in the characterization of molecular alterations in solid tumors. Review articles that describe the state-of-the-art on this topic are also encouraged.
Dr. Dario de Biase
Dr. Umberto Malapelle
Prof. Dr. Matteo Fassan
Guest Editor
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Keywords
- Next-generation sequencing
- Lung tumors
- Brain tumors
- Pancreatic tumors
- Liquid biopsy
- Thyroid tumors
- Colorectal carcinomas
- Melanoma
- Molecular techniques
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