Ultrasound Imaging in Medicine in 2025

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 949

Special Issue Editor


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Guest Editor
Department of Diagnostic Radiology, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark
Interests: diagnostic radiology; cancer imaging; medical ultrasound; Doppler techniques; CT-scanning; medical presentations; musculoskeletal imaging
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Special Issue Information

Dear Colleagues,

Ultrasound examinations are performed within almost all medical specialties and are of paramount value in clinical medicine and as research tools. Diagnostic ultrasounds as well as ultrasound guidance for biopsy, drainage, and tumor ablation have become an integral part of the clinical setting. The last ten years have seen an increase in new ultrasound techniques such as contrast-enhanced ultrasound (CEUS), elastography techniques, 3D ultrasound, image fusion with ultrasound, and methods for flow visualization such as the vector Doppler method. In terms of the technical aspects, transducer technology has also evolved tremendously. This Special Issue invites submissions of both original and review papers as well as technical and clinical papers pertaining to all aspects of ultrasound imaging.

Prof. Dr. Michael Bachmann Nielsen
Guest Editor

Manuscript Submission Information

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Keywords

  • 3D ultrasound
  • blood flow velocity
  • ultrasonography
  • contrast-enhanced ultrasound
  • elasticity imaging
  • endoscopic ultrasound
  • intervention

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Published Papers (1 paper)

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Research

21 pages, 2681 KiB  
Article
Analysing the Renal Vasculature Using Super-Resolution Ultrasound Imaging: Considerations for Clinical and Research Applications
by Amy McDermott, Nathalie Sarup Panduro, Iman Taghavi, Hans Martin Kjer, Stinne Byrholdt Søgaard, Michael Bachmann Nielsen, Jørgen Arendt Jensen and Charlotte Mehlin Sørensen
Diagnostics 2025, 15(12), 1515; https://doi.org/10.3390/diagnostics15121515 - 14 Jun 2025
Viewed by 354
Abstract
Background: Vascular imaging is essential for clinical practice, research, and the diagnosis and management of vascular diseases. Super-resolution ultrasound (SRUS) imaging is an emerging high-resolution imaging technique with broad applications in soft tissue vascular imaging. However, the impact of biological and clinical variables [...] Read more.
Background: Vascular imaging is essential for clinical practice, research, and the diagnosis and management of vascular diseases. Super-resolution ultrasound (SRUS) imaging is an emerging high-resolution imaging technique with broad applications in soft tissue vascular imaging. However, the impact of biological and clinical variables on its imaging accuracy is currently unknown. This study investigates these factors in an animal model and compares SRUS with contrast-enhanced µCT. Methods: Kidney scans from 29 Zucker rats (Zucker Diabetic Fatty and Zucker Lean) were retrospectively analysed. The left kidney was imaged in vivo using SRUS during microbubble infusion, then filled with Microfil and excised for ex vivo µCT. SRUS parameters and clinical variables were analysed, and SRUS scans were co-registered with µCT to compare vascular density measurements. Results: Mean arterial blood pressure and anaesthesia time showed significant linear relationships with SRUS microbubble detection and vascular track reconstruction. The anaesthesia time was also strongly correlated with vascular density measurement. Visualisation and velocity estimations of renal arteries were limited with SRUS. Ultrasound signal attenuation had significant impacts, particularly in cortical far-field imaging. Despite differences between kidney regions, the vascular density distribution did not differ considerably between SRUS and µCT datasets for whole-kidney imaging. Conclusions: This study outlines key factors SRUS users must consider for optimal technique use. Careful region selection and control of clinical variables ensure more reliable and comparable images. Further research is necessary to translate these findings from a rat model into clinical application. Full article
(This article belongs to the Special Issue Ultrasound Imaging in Medicine in 2025)
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