Multimodality Imaging of Pulmonary Hypertension

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 2392

Special Issue Editors


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Guest Editor
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK
Interests: clinical management of pulmonary hypertension; diagnosis and assessment of pulmonary hypertension with a focus on imaging

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Guest Editor
Department of Infection, Immunity and Cardiovascular Disease, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
Interests: clinical application of novel imaging techniques and analysis approaches in patients with cardiac and pulmonary disease

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Guest Editor
Division of Thoracic Radiology, Mayo Clinic, Rochester, NY, USA
Interests: clinical application of imaging techniques to quantify key aspects of pulmonary physiology

Special Issue Information

Dear Colleagues,

Pulmonary hypertension has many causes and remains a life-shortening condition. Making an accurate diagnosis is key in defining prognosis and treatment, as is the need for ongoing monitoring. Over the last 2 decades, there have been significant advances in imaging techniques, including the emergence of artificial intelligence approaches and an increasingly collaborative approach to research. This Special Issue summarises a range of imaging techniques and their current and potential applications in the assessment and ongoing monitoring or patients with pulmonary hypertension. Included are the application of approaches such as harnessing the power of AI, large data sets and genomics, the use of imaging tools to assess cardiac, lung, and vascular structure and function, and their application to improve our understanding of disease and aid clinical decision making.

Prof. Dr. David G. Kiely
Dr. Andrew J. Swift
Prof. Dr. David L. Levin
Guest Editors

Manuscript Submission Information

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Keywords

  • MRI
  • CT
  • scintigraphy
  • artificial intelligence
  • genomics
  • pulmonary arterial hypertension
  • pulmonary hypertension
  • chronic thromboembolic pulmonary hypertension
  • right ventricular function
  • micro-CT
  • 4D flow
  • imaging
  • COVID-19

Published Papers (1 paper)

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Research

15 pages, 2160 KiB  
Article
Application and Validation of the Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio in Patients with Ischemic and Non-Ischemic Cardiomyopathy
by Stanislav Keranov, Saskia Haen, Julia Vietheer, Wiebke Rutsatz, Jan-Sebastian Wolter, Steffen D. Kriechbaum, Beatrice von Jeinsen, Pascal Bauer, Khodr Tello, Manuel Richter, Oliver Dörr, Andreas J. Rieth, Holger Nef, Christian W. Hamm, Christoph Liebetrau, Andreas Rolf and Till Keller
Diagnostics 2021, 11(12), 2188; https://doi.org/10.3390/diagnostics11122188 - 24 Nov 2021
Cited by 4 | Viewed by 1790
Abstract
The main aim of this study was to assess the prognostic utility of TAPSE/PASP as an echocardiographic parameter of maladaptive RV remodeling in cardiomyopathy patients using cardiac magnetic resonance (CMR) imaging. Furthermore, we sought to compare TAPSE/PASP to TAPSE. The association of the [...] Read more.
The main aim of this study was to assess the prognostic utility of TAPSE/PASP as an echocardiographic parameter of maladaptive RV remodeling in cardiomyopathy patients using cardiac magnetic resonance (CMR) imaging. Furthermore, we sought to compare TAPSE/PASP to TAPSE. The association of the echocardiographic parameters TAPSE/PASP and TAPSE with CMR parameters of RV and LV remodeling was evaluated in 111 patients with ischemic and non-ischemic cardiomyopathy and cut-off values for maladaptive RV remodeling were defined. In a second step, the prognostic value of TAPSE/PASP and its cut-off value were analyzed regarding mortality in a validation cohort consisting of 221 patients with ischemic and non-ischemic cardiomyopathy. A low TAPSE/PASP (<0.38 mm/mmHg) and TAPSE (<16 mm) were associated with a lower RVEF and a long-axis RV global longitudinal strain (GLS) as well as higher RVESVI, RVEDVI and NT-proBNP. A low TAPSE/PASP, but not TAPSE, was associated with a lower LVEF and long-axis LV GLS, and a higher LVESVI, LVEDVI and T1 relaxation time at the interventricular septum and the RV insertion points. Furthermore, in the validation cohort, low TAPSE/PASP was associated with a higher mortality and TAPSE/PASP was an independent predictor of mortality. TAPSE/PASP is a predictor of maladaptive RV and LV remodeling associated with poor outcomes in cardiomyopathy patients. Full article
(This article belongs to the Special Issue Multimodality Imaging of Pulmonary Hypertension)
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