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Diagnostics
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New Diagnostic Technologies in Urological Care
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New Diagnostic Technologies in Urological Care

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 1331

Special Issue Editors

Dr. Alberto Piana

E-Mail Website
Guest Editor
1. Department of Urology, University of Turin, 10043 Turin, Italy
2. Department of Urology, Romolo Hospital, 88821 Rocca di Neto, Italy
Interests: kidney transplantation; urologic oncology; endourology; urolithiasis; laparoscopic urology; prostate; prostate cancer
Dr. Enrico Checcucci

E-Mail Website
Guest Editor
Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, Strada Provinciale 142, km 3, 95, 10060 Candiolo, Italy
Interests: urologic oncology; prostate cancer; urotechnology
Special Issues, Collections and Topics in MDPI journals
Dr. Michele Di Dio

E-Mail Website
Guest Editor
Division of Urology, Department of Surgery, SS Annunziata Hospital, 87100 Cosenza, Italy
Interests: renal diseases; urologic diseases; kidney diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to investigate new technologies and scenarios in the field of urology.

This Special Issue invites original research articles, review papers, and clinical studies that enrich our knowledge about the newest technologies available for an early and accurate diagnosis of pathological conditions in urology. We encourage submissions focusing on topics such as urologic cancers, prediction of surgical challenges, and the use of technology for patient-tailored clinical follow-ups.

To ensure the highest quality of publications, we kindly request that authors refrain from submitting mini-reviews and case reports for this Special Issue. Instead, we seek in-depth research articles and comprehensive reviews that present novel findings and insights into “uro-technology”.

By bringing together leading experts and researchers in the field, this Special Issue aims to foster interdisciplinary discussions and promote collaborations to address the pressing issues faced in urology. We believe this collection of articles will serve as a valuable resource for clinicians and researchers involved in improving their clinical practice.

Dr. Alberto Piana
Dr. Enrico Checcucci
Dr. Michele Di Dio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urological care
  • prostate cancer
  • diagnostics technologies
  • surgical challenges
  • laparoscopic urology

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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13 pages, 920 KiB  
Article
Predicting Urosepsis in Ureteral Calculi: External Validation of Hu’s Nomogram and Identification of Novel Risk Factors
by Yuka Sugizaki, Takanobu Utsumi, Naoki Ishitsuka, Takahide Noro, Yuta Suzuki, Shota Iijima, Takatoshi Somoto, Ryo Oka, Takumi Endo, Naoto Kamiya and Hiroyoshi Suzuki
Diagnostics 2025, 15(9), 1104; https://doi.org/10.3390/diagnostics15091104 - 26 Apr 2025
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Abstract
Background/Objectives: Acute obstructive pyelonephritis caused by ureteral calculi is a severe urological emergency that can rapidly progress to life-threatening complications, including urosepsis. Early risk stratification is critical for timely intervention and improved patient outcomes. Although Hu’s nomogram has been proposed as a [...] Read more.
Background/Objectives: Acute obstructive pyelonephritis caused by ureteral calculi is a severe urological emergency that can rapidly progress to life-threatening complications, including urosepsis. Early risk stratification is critical for timely intervention and improved patient outcomes. Although Hu’s nomogram has been proposed as a predictive tool for urosepsis, its external validation remains limited. This study aims to validate Hu’s nomogram in an independent cohort and identify novel clinical and imaging predictors of urosepsis. Methods: This retrospective cohort study included 341 patients diagnosed with ureteral calculi who underwent surgical intervention at a single institution between January 2019 and October 2023. Clinical, laboratory, and imaging data were collected. Univariate and multivariate logistic regression analyses were performed to identify independent predictors of urosepsis. The predictive accuracy of Hu’s nomogram was evaluated using receiver operating characteristic curve analysis. Results: Among 341 patients, 66 (19.4%) developed urosepsis. Multivariate analysis identified female gender, corticosteroid use, lower platelet count, elevated C-reactive protein levels, positive urine white blood cell count, lower computed tomography attenuation values of calculi, and higher computed tomography attenuation values of hydronephrosis as independent predictors of urosepsis. Hu’s nomogram demonstrated a strong predictive performance (area under the curve: 0.761; 95% CI: 0.701–0.821), reaffirming its clinical utility for risk stratification. Conclusions: This study provides an external validation of Hu’s nomogram and identifies novel risk factors for urosepsis prediction, including corticosteroid use and imaging-based parameters. Incorporating these findings into clinical practice may enhance early risk stratification, facilitate timely interventions, and ultimately improve patient outcomes. Full article
(This article belongs to the Special Issue New Diagnostic Technologies in Urological Care)
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Review

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14 pages, 716 KiB  
Review
The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses
by Catalin-Andrei Bulai, Razvan-Dragos Multescu, Petrisor-Aurelian Geavlete, Ana Maria Andreea Punga, Adrian Militaru, Bogdan-Gabriel Buzescu, Cosmin-Victor Ene, Cristian Mares and Bogdan-Florin Geavlete
Diagnostics 2025, 15(4), 416; https://doi.org/10.3390/diagnostics15040416 - 8 Feb 2025
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Abstract
Transurethral enucleation (TUE) has revolutionized the management of benign prostatic obstruction (BPO), offering a minimally invasive solution with superior efficacy across all prostate sizes. This review explores the advancements in TUE techniques, including Holmium Laser Enucleation of the Prostate (HoLEP), Thulium Laser Enucleation [...] Read more.
Transurethral enucleation (TUE) has revolutionized the management of benign prostatic obstruction (BPO), offering a minimally invasive solution with superior efficacy across all prostate sizes. This review explores the advancements in TUE techniques, including Holmium Laser Enucleation of the Prostate (HoLEP), Thulium Laser Enucleation of the Prostate (ThuLEP), and bipolar enucleation, highlighting their clinical benefits, safety profiles, and long-term outcomes. Compared to traditional approaches such as transurethral resection of the prostate (TURP) and open prostatectomy, TUE has been associated with reduced complication rates, shorter recovery times, and durable symptom relief. The manuscript also examines patient-centered considerations, such as quality of life improvements and preservation of sexual function, which contribute to high patient satisfaction. Furthermore, the economic advantages of TUE, driven by reduced retreatment rates and healthcare costs, underscore its value for both patients and healthcare systems. Emerging innovations, including artificial intelligence (AI), promise to further enhance procedural planning, surgical precision, and training pathways. Efforts to expand global access through cost-effective adaptations like bipolar enucleation and targeted training initiatives are paving the way for wider adoption of TUE. With its adaptability, technological advancements, and focus on patient outcomes, TUE is poised to become the global standard of care in BPO management. Full article
(This article belongs to the Special Issue New Diagnostic Technologies in Urological Care)
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