Advances in Thyroid Imaging

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 7056

Special Issue Editor


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Guest Editor
Department of Nuclear Medicine, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, 680 Gukchaebosangro, Junggu, Daegu 41944, Korea
Interests: thyroid cancer, radionuclide therapy, functional imaging, molecular imaging, PET, SPECT

Special Issue Information

Dear Colleagues,

The field of thyroid imaging is being continuously innovated, and brand-new knowledge and cutting-edge clinical techniques for diagnosis have been reported. Thyroid imaging using a radionuclide was a pioneer of functional imaging, and radioiodine was used for the diagnosis and treatment of thyroid disease. Due to the recent technical advancement of SPECT, PET, MRI and ultrasonography, diverse information about the disease can be obtained. In thyroid cancer, a different tracer provides a different piece of valuable information, and this can be translated for therapeutic approaches. In addition, recent reports showed the application of artificial intelligence in thyroid imaging.

In this Special Issue, new, original, advanced and innovative studies on diagnostic techniques including functional imaging, structural imaging and artificial intelligence will be considered for publication. Your valuable studies in all areas of thyroid imaging will be welcomed. This Special Issue aims to support researchers who are investigating the diseases of the thyroid gland for better clinical diagnosis and new methods, resulting in the advancement of diagnostics.

Dr. Chae Moon Hong
Guest Editor

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Keywords

  • Radioiodine SPECT/CT
  • I-124 PET
  • F-18 FDG
  • F-18 F-DOPA
  • Ga-68 somatostatin
  • Ga-68 PSMA
  • Computed tomography
  • Magnetic Resonance Imaging
  • Ultrasonography
  • Artificial intelligence

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Published Papers (2 papers)

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Research

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13 pages, 1736 KiB  
Article
Diagnostic Performance of 99mTc-Methoxy-Isobuty-Isonitrile (MIBI) for Risk Stratification of Hypofunctioning Thyroid Nodules: A European Multicenter Study
by Simone Agnes Schenke, Alfredo Campennì, Murat Tuncel, Gianluca Bottoni, Sait Sager, Tatjana Bogovic Crncic, Damir Rozic, Rainer Görges, Pinar Pelin Özcan, Daniel Groener, Hubertus Hautzel, Rigobert Klett, Michael Christoph Kreissl and Luca Giovanella
Diagnostics 2022, 12(6), 1358; https://doi.org/10.3390/diagnostics12061358 - 31 May 2022
Cited by 13 | Viewed by 3096
Abstract
99mTc-MIBI (MIBI) imaging is able to exclude malignancy of hypofunctioning thyroid nodules (TNs) with high probability but false positive results are frequent due to low specificity. Therefore, pre-test selection of appropriate TNs is crucial. For image evaluation visual and semiquantitative methods (Washout [...] Read more.
99mTc-MIBI (MIBI) imaging is able to exclude malignancy of hypofunctioning thyroid nodules (TNs) with high probability but false positive results are frequent due to low specificity. Therefore, pre-test selection of appropriate TNs is crucial. For image evaluation visual and semiquantitative methods (Washout index, WOInd) are used. Aim of this study was to evaluate the diagnostic performance of MIBI imaging in hypofunctioning TNs with indeterminate fine-needle aspiration cytology results in a multicentric European setting. Patients with hypofunctioning TNs, EU-TIRADS 4 or 5, Bethesda III/IV and MIBI imaging were included. For visual evaluation the intensity of MIBI uptake in the TN was compared to normal thyroid tissue. 358 patients with 365 TNs (n = 68 malignant) were included. Planar imaging (SPECT) showed a sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 96% (94%), 21% (22%), 22% (15%), 96% (96%), and 35% (32%). The WOInd (38.9% of all cases, optimal cutoff: −19%) showed a sens 100% (spec 89%, PPV 82%, NPV 100%, ACC 93%). For hypofunctioning TNs at intermediate or high risk with indeterminate cytology, a MIBI negative result on visual evaluation is an effective tool to rule-out thyroid malignancy. The semi-quantitative method could considerably improve overall diagnostic performance of MIBI imaging. Full article
(This article belongs to the Special Issue Advances in Thyroid Imaging)
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Review

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13 pages, 698 KiB  
Review
Quantitative Diagnosis Progress of Ultrasound Imaging Technology in Thyroid Diffuse Diseases
by Jing Huang and Jiaqi Zhao
Diagnostics 2023, 13(4), 700; https://doi.org/10.3390/diagnostics13040700 - 13 Feb 2023
Cited by 5 | Viewed by 3249
Abstract
High-frequency ultrasound (HFUS), the imaging modality of choice for thyroid screening, is most commonly used in the study of diffuse thyroid disease (DTD) with Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). DTD can involve thyroid function and severely affect life quality, so early [...] Read more.
High-frequency ultrasound (HFUS), the imaging modality of choice for thyroid screening, is most commonly used in the study of diffuse thyroid disease (DTD) with Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). DTD can involve thyroid function and severely affect life quality, so early diagnosis is important for the development of timely clinical intervention strategies. Previously, the diagnosis of DTD relied on qualitative ultrasound imaging and related laboratory tests. In recent years, with the development of multimodal imaging and intelligent medicine, ultrasound and other diagnostic imaging techniques have gradually become more widely used for quantitative assessment of the structure and function of DTD. In this paper, we review the current status and progress of quantitative diagnostic ultrasound imaging techniques for DTD. Full article
(This article belongs to the Special Issue Advances in Thyroid Imaging)
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