Recent Advances in Precision Radiotherapy of Cancer

Dear Colleagues,

The trend of cancer incidence is increasing worldwide. About 80% of cancer patients receive radiotherapy (RT) for their treatment externally or internally. However, in spite of years and years of hard work among scientists, there are still many unsolved questions in the field of radiation therapy. It took about 50 years for us to be able to use high-energy photons generated from Cobalt-60 or linear accelerators for treatment of deep-seated tumors. There has been a significant technical advancement during the last two decades in external radiation dose delivery such as intensity modulated radiotherapy (IMRT), intraoperative RT (IORT), image-guided RT (IGRT), stereotactic body RT (SBRT), and different fractionation schemes, such as hyper- and hypo-fractionation, to spare normal tissues as much as possible and achieve better radiotherapy outcomes. The introduction of three‐ and four-dimensional conformal radiation therapy (3D or 4D-CRT) has been a major advancement in radiotherapy, and it is now possible to plan and prescribe radiation doses with desired dose distribution to the entire tumor using computer-aided techniques. New radiation treatment modalities such as neutrons and proton and ion therapy continue to represent a major challenge in the management of localized human cancer. Therefore, we are still far from achieving a personalized cancer radiotherapy.

Diagnostics has decided to publish a Special Issue with the aim to collect a series of research articles and reviews from a diverse group in the scientific community to share their research regarding radiotherapy in cancer. Therefore, I cordially invite you to take part in this Special Issue with a scientific contribution.

Prof. Dr. Hossein Mozdarani
Guest Editor

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