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Diagnostics
Special Issues
Innovation in Gastrointestinal Endoscopy
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Innovation in Gastrointestinal Endoscopy

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 4741

Special Issue Editors

Dr. Antonio Facciorusso

E-Mail Website
Guest Editor
Endoscopy Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy
Interests: gastrointestinal endoscopy; endoscopic ultrasound; liver cancer; pancreatology
Special Issues, Collections and Topics in MDPI journals
Dr. Daryl Ramai

E-Mail Website
Guest Editor
Division of Gastroenterology, Hepatology and Nutrition, The University of Utah, Salt Lake City, UT, USA
Interests: endoscopy; statistics; clinical epidemiology; clinical research; gastroenterology

Special Issue Information

Dear Colleagues,

Gastrointestinal endoscopy covers both diagnosis and therapy. Due to its diagnostic accuracy and minimal invasiveness, several innovations have been made within the last several years, including artificial intelligence and endoscopic tumor resection.

The presently announced Special Issue entitled “Innovation in Gastrointestinal Endoscopy” will encompass research articles, case presentations, literature reviews, and meta-analyses concerning the latest advancements in the field.

This Special Issue aims to enhance the learning interface for newly trained gastroenterologists, experienced gastroenterologists and endoscopists in general who want to know about more advanced procedures such as endoscopic ultrasound-guided interventions, endoscopic dissection, and other advanced techniques.

This Special Issue will explore, but is not restricted to, the following topics:

  • Endoscopic ultrasound-guided sampling and interventions such as newer lumen-apposing metal stents;
  • Endoscopic retrograde cholangiopancreatography;
  • Endoscopic mucosal resection and endoscopic submucosal dissection;
  • Screening and diagnostic colonoscopy;
  • Endoscopic diagnosis and treatment of reflux disease and achalasia.

We hope that the published data will contribute to scientific discussion concerning these global health problems.

Dr. Antonio Facciorusso
Dr. Daryl Ramai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastrointestinal endoscopy
  • endoscopic therapies
  • peroral endoscopic myotomy
  • endoscopic submucosal dissection
  • endoscopic ultrasound
  • EUS
  • LAMS
  • endoscopic mucosal resection
  • endoscopic drainage
  • screening

Published Papers (3 papers)

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Research

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10 pages, 433 KiB  
Article
Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study
by Germana de Nucci, Tommaso Gabbani, Giovanna Impellizzeri, Simona Deiana, Paolo Biancheri, Laura Ottaviani, Leonardo Frazzoni, Enzo Domenico Mandelli, Paola Soriani, Maurizio Vecchi, Gianpiero Manes and Mauro Manno
Diagnostics 2023, 13(11), 1842; https://doi.org/10.3390/diagnostics13111842 - 25 May 2023
Viewed by 899
Abstract
Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this [...] Read more.
Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC. Full article
(This article belongs to the Special Issue Innovation in Gastrointestinal Endoscopy)
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Review

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17 pages, 319 KiB  
Review
New Perspectives in Endoscopic Treatment of Gastroesophageal Reflux Disease
by Federica Calabrese, Valeria Poletti, Francesco Auriemma, Danilo Paduano, Carmine Gentile, Antonio Facciorusso, Gianluca Franchellucci, Alessandro De Marco, Luca Brandaleone, Andrew Ofosu, Jayanta Samanta, Daryl Ramai, Luca De Luca, Abed Al-Lehibi, Walter Zuliani, Cesare Hassan, Alessandro Repici and Benedetto Mangiavillano
Diagnostics 2023, 13(12), 2057; https://doi.org/10.3390/diagnostics13122057 - 14 Jun 2023
Viewed by 2270
Abstract
Gastroesophageal reflux disease has a high incidence and prevalence in the general population. Clinical manifestations are heterogenous, and so is the response to medical treatment. Proton pump inhibitors are still the most common agents used to control reflux symptoms and for healing esophagitis, [...] Read more.
Gastroesophageal reflux disease has a high incidence and prevalence in the general population. Clinical manifestations are heterogenous, and so is the response to medical treatment. Proton pump inhibitors are still the most common agents used to control reflux symptoms and for healing esophagitis, but they are not a one-size-fits-all solution for the disease. Patients with persistent troublesome symptoms despite medical therapy, those experiencing some adverse drug reaction, or those unwilling to take lifelong medications deserve valid alternatives. Anti-reflux Nissen fundoplication is an effective option, but the risk of adverse events has limited its spread. In recent years, advancements in therapeutic endoscopy have been made, and three major endoluminal alternatives are now available, including (1) the delivery of radiofrequency energy to the esophago–gastric junction, (2) transoral incisionless fundoplication (TIF), and (3) anti-reflux mucosal interventions (ARMI) based on mucosal resection (ARMS) and mucosal ablation (ARMA) techniques to remodel the cardia. Endoscopic techniques have shown interesting results, but their diffusion is still limited to expert endoscopists in tertiary centers. This review discusses the state of the art in the endoscopic approach to gastroesophageal reflux disease. Full article
(This article belongs to the Special Issue Innovation in Gastrointestinal Endoscopy)

Other

Jump to: Research, Review

8 pages, 1514 KiB  
Case Report
Usefulness of Contrast-Enhanced Endoscopic Ultrasound (CH-EUS) to Guide the Treatment Choice in Superficial Rectal Lesions: A Case Series
by Giulia Gibiino, Monica Sbrancia, Cecilia Binda, Chiara Coluccio, Stefano Fabbri, Paolo Giuffrida, Graziana Gallo, Luca Saragoni, Roberta Maselli, Alessandro Repici and Carlo Fabbri
Diagnostics 2023, 13(13), 2267; https://doi.org/10.3390/diagnostics13132267 - 04 Jul 2023
Cited by 2 | Viewed by 1001
Abstract
Introduction: Large rectal lesions can conceal submucosal invasion and cancer nodules. Despite the increasing diffusion of high-definition endoscopes and the importance of an accurate morphological evaluation, a complete assessment in this setting can be challenging. Endoscopic ultrasound (EUS) plays an established role in [...] Read more.
Introduction: Large rectal lesions can conceal submucosal invasion and cancer nodules. Despite the increasing diffusion of high-definition endoscopes and the importance of an accurate morphological evaluation, a complete assessment in this setting can be challenging. Endoscopic ultrasound (EUS) plays an established role in the locoregional staging of rectal cancer, although this technique has a tendency toward the over-estimation of the loco-regional (T) staging. However, there are still few data on contrast-enhanced endoscopic ultrasound (CH-EUS), especially if this ancillary technique may increase the accuracy for predicting invasive nodules among large rectal lesions. Material and Methods: Consecutive large (≥20 mm) superficial rectal lesions with high-definition endoscopy, characterized by focal areas suggestive for invasive cancer/2B type according to JNET classification, were considered for additional standardized evaluation via CH-EUS with Sonovue ©. Results: From 2020 to 2023, we evaluated 12 consecutive superficial rectal lesions with sizes ranging from 20 to 180 mm. This evaluation provided additional elements to support the therapeutic decision made. Lesions were treated with surgical (3/12) or endoscopic treatment (9/12) according to their morphology and CH-EUS evaluation. Conclusion: Contrast-enhanced endoscopic ultrasound can provide an additional evaluation for large and difficult-to-classify rectal lesions. In our experience, CH-EUS staging corresponded to the final pathological stages in 9/12 (75%) lesions, improving the distinction between T1 and T2 lesions. Larger prospective studies and randomized trials should be conducted to support and standardize this approach. Full article
(This article belongs to the Special Issue Innovation in Gastrointestinal Endoscopy)
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