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Diagnostics
Special Issues
Echocardiography in the Intensive Care Unit
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Echocardiography in the Intensive Care Unit

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 619

Special Issue Editor

Prof. Dr. Carlo Caiati

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Guest Editor
Cardiovascular Division, University of Bari, 70123 Bari, Italy
Interests: cardiomyopathy; prognosis; echocardiography; systolic and diastolic cardiac function; long term outcome; cardiac transplantation; heart failure
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As a non-invasive imaging modality, echocardiography is a vital tool in the intensive care setting, which provides a real-time assessment of cardiac function, hemodynamics, and structural abnormalities. This Special Issue entitled "Echocardiography in the Intensive Care Unit" aims to bring together articles on cutting-edge research and clinical applications of echocardiography in the ICU. Articles may cover topics such as the use of echocardiography for early diagnosis of coronary artery disease, assessment of myocardial ischemia and viability, and monitoring of cardiac function in patients with sepsis, shock, and acute respiratory distress syndrome, etc. We believe it will contribute to the continued advancement of echocardiography practice in the intensive care setting, providing new insights for clinicians and researchers.

Prof. Dr. Carlo Caiati
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • echocardiography
  • intensive care unit (ICU)
  • critical care
  • cardiac function
  • coronary artery disease
  • sepsis
  • shock

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Published Papers (1 paper)

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Research

15 pages, 1569 KiB  
Article
Characterisation of Post-Sepsis Cardiomyopathy Using Cardiovascular Magnetic Resonance
by Samuel Malomo, Thomas Oswald, Edward Stephenson, Anthony Yip, Thomas Alway, Stanislav Hadjivassilev, Steven Coombs, Susan Ellery, Joon Lee, Rachael James, Claire Phillips, Barbara Philips, David Hildick-Smith, Victoria Parish and Alexander Liu
Diagnostics 2025, 15(8), 997; https://doi.org/10.3390/diagnostics15080997 - 14 Apr 2025
Cited by 1 | Viewed by 417
Abstract
Background: Post-sepsis cardiomyopathy is associated with an increased risk of adverse cardiovascular outcomes. It remains poorly understood, which limits therapeutic development. This study characterised post-sepsis cardiomyopathy using cardiovascular magnetic resonance (CMR) imaging. Methods: Patients admitted with acute sepsis and suspected cardiac injury or [...] Read more.
Background: Post-sepsis cardiomyopathy is associated with an increased risk of adverse cardiovascular outcomes. It remains poorly understood, which limits therapeutic development. This study characterised post-sepsis cardiomyopathy using cardiovascular magnetic resonance (CMR) imaging. Methods: Patients admitted with acute sepsis and suspected cardiac injury or heart failure who subsequently (47 days [IQR: 22–122]) underwent CMR at a UK tertiary cardiac centre were included. Age- and gender-matched controls (n = 16) were also included. Subjects underwent CMR at 1.5 Tesla with cines, native T1- and T2-mapping, and late gadolinium enhancement (LGE) imaging. Results: Of the 22 post-sepsis patients (age 50 ± 13 years; 64% males), 13 patients (59%) had left ventricular (LV) dilatation. Patients had significantly elevated left ventricular (LV) end-diastolic and end-systolic volume indices compared to controls (p = 0.011 and p = 0.013, respectively). Eleven patients (50%) had LV systolic dysfunction (ejection fraction < 50%), most of whom (8/11) had non-ischaemic patterns of LGE (n = 7 mid-wall; n = 1 mid-wall/patchy). In the eleven patients with preserved LV systolic function (ejection fraction ≥ 50%), three patients (27%) had significant LGE (n = 1 mid-wall; n = 1 subepicardial/mid-wall; n = 1 patchy). Compared to controls, patients had elevated septal native myocardial T1 values (p < 0.001) but similar septal native myocardial T2 values (p = 0.090), suggesting the presence of myocardial fibrosis without significant oedema. Conclusions: Post-sepsis cardiomyopathy is characterised by LV dilatation, systolic dysfunction, and myocardial fibrosis in a non-ischaemic distribution. Significant myocardial oedema is not prominent several weeks post-recovery. Further work is needed to test these findings on a multi-centre basis and to develop novel therapies for post-sepsis cardiomyopathy. Full article
(This article belongs to the Special Issue Echocardiography in the Intensive Care Unit)
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