Editorial Board Members’ Collection Series: Companion Diagnostic Test for Precision Medicine in Gynecologic Cancers

Dear Colleagues,

Background

Precision medicine is a novel cancer treatment approach that specifically targets the patients’ clinical features with genetic or proteomic alterations. In gynecologic cancers, one of the most successful examples is the use of poly (ADP-ribose) and polymerase (PARP) inhibitors in advanced ovarian cancer patients who have the BRCA mutation or homologous recombination deficiency (HRD). Another example is the use of anti-programmed cell death-1 (PD1)/ligand 1 (PD-L1) in advanced or recurrent endometrial cancers that harbor mismatch repair (MMR) deficiency, as well as cervical cancers that have PD-L1 expression. Precision medicine may potentially improve the survival outcomes of these patients, maintain their quality of life, and provide an alternative treatment option, especially in those who are resistant to conventional chemotherapy. Therefore, a reliable test is required to select the right patients for the treatment.

Scope

This Special Issue aims to collect papers on diagnostic tests related to the application of precision medicine in gynecologic cancers. We invite authors to submit their original research including preclinical, translational studies, and clinical trials. Review articles and protocol designs may also be considered. Potential topics include but are not limited to:

• Molecular assessments such as liquid biopsy and tumor molecular profiling;
• Cutting-edge imaging techniques such as radiomics and artificial intelligence;
• Translational models to correlate patients’ responses to targeted therapy and immunotherapy.

Dr. Ka Yu Tse
Dr. Kelvin Y. K. Chan
Guest Editors

Dr. Elaine Lee
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.