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Diagnostics
Special Issues
Diagnosis and Management of Osteoarthritis
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Diagnosis and Management of Osteoarthritis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: closed (30 June 2025) | Viewed by 305

Special Issue Editor

Dr. Robert Karpiński

E-Mail Website
Guest Editor
Department of Machine Design and Mechatronics, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland
Interests: structural analysis; biomechanics; finite element analysis; finite element method; fracture; rapid prototyping; biomechanical engineering; biomaterial engineering; trauma surgery; sports injuries
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Osteoarthritis (OA) is a leading cause of disability worldwide, affecting millions of individuals and posing a significant challenge to healthcare systems. This degenerative joint disease not only limits mobility and impairs quality of life but also imposes substantial economic and social burdens. The early diagnosis and effective management is OA are critical to improving outcomes and mitigating the long-term consequences of this condition.

This Special Issue in Diagnostics aims to explore the latest advances in the diagnosis, monitoring, and management of osteoarthritis. Topics will include innovative imaging techniques, biomarkers for early detection, and therapeutic interventions designed to preserve joint function and reduce pain. Contributions focusing on multidisciplinary approaches to care, combining traditional and emerging technologies, are particularly welcome.

A growing body of research emphasizes the importance of alternative diagnostic methods for detecting early degenerative changes. These include vibroarthrography, advanced magnetic resonance imaging (MRI), and novel biochemical assays. Such approaches have the potential to identify OA at a subclinical stage, enabling timely intervention and personalized treatment strategies. This Special Issue seeks to highlight these emerging techniques and their integration into routine clinical practice.

Dr. Robert Karpiński
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • osteoarthritis
  • early detection
  • joint degeneration
  • alternative diagnostic methods
  • vibroarthrography
  • magnetic resonance imaging (MRI)
  • biomarkers
  • non-invasive diagnostics
  • osteoarthritis management
  • degenerative joint disease

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Published Papers (1 paper)

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Research

13 pages, 2552 KiB  
Article
The Diagnosis of and Preoperative Planning for Rapidly Osteoarthritis of the Hip: The Role of Sagittal Spinopelvic Geometry and Anterior Acetabular Wall Deficiency—A Prospective Observational Study
by Andrei Oprișan, Andrei Marian Feier, Sandor Gyorgy Zuh, Octav Marius Russu and Tudor Sorin Pop
Diagnostics 2025, 15(13), 1647; https://doi.org/10.3390/diagnostics15131647 - 27 Jun 2025
Viewed by 98
Abstract
Background/Objectives: Rapidly progressive osteoarthritis of the hip (RPOH) has unique diagnostic and surgical challenges due to rapid joint degeneration and acetabular structural alterations. This study aimed to investigate correlations between preoperative spinopelvic geometry and anterior acetabular wall bone stock deficiency in RPOH [...] Read more.
Background/Objectives: Rapidly progressive osteoarthritis of the hip (RPOH) has unique diagnostic and surgical challenges due to rapid joint degeneration and acetabular structural alterations. This study aimed to investigate correlations between preoperative spinopelvic geometry and anterior acetabular wall bone stock deficiency in RPOH patients and introduce an advanced imaging measurement techniques for cases with amputated femoral heads. Methods: A prospective observational study was conducted that enrolled 85 patients, comprising 40 with unilateral RPOH (Zazgyva Grade II or III) and 45 controls with primary osteoarthritis (OA). Preoperative spino-pelvic parameters (pelvic tilt—PT, sacral slope—SS, lumbar lordosis—LL, and T1 pelvic angle) and acetabular anterior wall characteristics (anterior center edge angle—ACEA, anterior wall index—AWI, and anterior acetabular surface area—AASA) were measured using standardized radiographic and CT imaging protocols, including a new methodology for acetabular center estimation in femoral head-amputated cases. Results: Significant differences were identified between RPOH and primary OA patients in the PT (22.5° vs. 18.9°, p = 0.032), SS (37.8° vs. 41.1°, p = 0.041), T1 pelvic angle (14.3° vs. 11.8°, p = 0.018), and anterior center edge angle (25.3° vs. 29.7°, p = 0.035). RPOH patients exhibited pronounced spinopelvic misalignment and anterior acetabular deficiencies. Conclusions: RPOH is associated with spinopelvic misalignment and anterior acetabular wall deficiency. Accurate preoperative diagnosis imaging and personalized surgical approaches specifically addressing acetabular bone stock deficiencies are mandatory in these cases. Full article
(This article belongs to the Special Issue Diagnosis and Management of Osteoarthritis)
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