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Announcements
6 May 2026
Head and Neck Cancer Awareness Month, April 2026
As part of its continued efforts to support impactful cancer research and foster scientific dialogue, MDPI is spotlighting head and neck cancer in this edition. Encompassing a diverse group of malignancies affecting the oral cavity, pharynx, and larynx, head and neck cancers collectively account for over 900,000 new cases and more than 400,000 deaths globally each year.
In recent years, shifting epidemiological patterns, particularly the rise of HPV-associated cancers, have introduced new challenges and opportunities in both research and clinical practice. These developments call for deeper insights into disease mechanisms, as well as more precise approaches to diagnosis, treatment, and patient stratification.
By bringing together cutting-edge research, focused Special Issues, and an expert-led webinar, MDPI journals aim to continue to facilitate knowledge exchange and highlight emerging advances in the field. These efforts play an important role in advancing innovation, improving early detection and therapeutic strategies, and ultimately enhancing outcomes for patients worldwide.

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Keynote speakers |
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Dr. Kousik Kumar Kesh, |
Prof. Dr. Richard Yuxiong Su, |
Dr. Jennifer Anderson, |
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Dr. Jay J. Liao, |
Prof. Dr. Wendell G. Yarbrough, |
Dr. Joshua D. Smith, |
Register for this webinar for free here!

“Enhancing Patient Outcomes in Head and Neck Cancer Radiotherapy: Integration of Electronic Patient-Reported Outcomes and Artificial Intelligence-Driven Oncology Care Using Large Language Models”
by ChihYing Liao, ChinNan Chu, TingChun Lin, TzuYao Chou and MengHsiun Tsai
Cancers 2025, 17(14), 2345; https://doi.org/10.3390/cancers17142345
“Advancing Head and Neck Cancer Therapies: From Conventional Treatments to Emerging Strategies”
by Aleksandra Mordzińska-Rak, Ilona Telejko, Grzegorz Adamczuk, Tomasz Trombik, Andrzej Stepulak and Ewa Błaszczak
Biomedicines 2025, 13(5), 1046; https://doi.org/10.3390/biomedicines13051046
“The Role of Dysphagia on Head and Neck Cancer Patients’ Quality of Life, Functional Disabilities and Psychological Distress: Outcomes of Cancer Rehabilitation from an Observational Single-Center Study”
by Špela Matko, Christina Knauseder, David Riedl, Vincent Grote, Michael J. Fischer, Samuel Moritz Vorbach, Karin Pfaller-Frank, Wilhelm Frank and Thomas Licht
Curr. Oncol. 2025, 32(4), 220; https://doi.org/10.3390/curroncol32040220
“PDLIM3 Regulates Migration and Invasion of Head and Neck Squamous Cell Carcinoma via YAP–Mediated Epithelial–Mesenchymal Transition”
by Fan Yang, Ying Zhou, You Zhang, Weideng Wei, Fei Huang, Dan Yang, Yixin Zhang, Ruiyang Zhang, Xiaoqiang Xia, Qianming Chen et al.
Int. J. Mol. Sci. 2025, 26(7), 3147; https://doi.org/10.3390/ijms26073147
“Inflammatory Biomarkers and Oral Health Disorders as Predictors of Head and Neck Cancer: A Retrospective Longitudinal Study”
by Amr Sayed Ghanem, Kitti Sipos, Ágnes Tóth and Attila Csaba Nagy
Int. J. Mol. Sci. 2025, 26(5), 2279; https://doi.org/10.3390/ijms26052279
“Trends in Incidence and Mortality of Head and Neck Cancer Subsites Among Elderly Patients: A Population-Based Analysis”
by Małgorzata Wierzbicka, Wioletta Pietruszewska, Adam Maciejczyk and Jarosław Markowski
Cancers 2025, 17(3), 548; https://doi.org/10.3390/cancers17030548
“Recurrent and Metastatic Head and Neck Cancer: Mechanisms of Treatment Failure, Treatment Paradigms, and New Horizons”
by William T. Barham, Marshall Patrick Stagg, Rula Mualla, Michael DiLeo and Sagar Kansara
Cancers 2025, 17(1), 144; https://doi.org/10.3390/cancers17010144
“Identification of Biomarkers for Diagnosis and Prognosis of Head and Neck Cancer: Bioinformatics Approach”
by Alexandra Fernandes and Rui Vitorino
Targets 2024, 2(4), 470-480; https://doi.org/10.3390/targets2040026
“Clinical Evidence of Methods and Timing of Proper Follow-Up for Head and Neck Cancers”
by Riccardo Gili, Simone Caprioli, Paola Lovino Camerino, Gianluca Sacco, Tommaso Ruelle, Daria Maria Filippini, Silvia Pamparino, Stefania Vecchio, Filippo Marchi, Lucia Del Mastro et al.
Onco 2024, 4(4), 275-286; https://doi.org/10.3390/onco4040020
“Artificial Intelligence in Head and Neck Cancer: Innovations, Applications, and Future Directions”
by Tuan D. Pham, Muy-Teck Teh, Domniki Chatzopoulou, Simon Holmes and Paul Coulthard
Curr. Oncol. 2024, 31(9), 5255-5290; https://doi.org/10.3390/curroncol31090389
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“The Advances in Proton Therapy in Head-and-Neck Cancers” |
“Decoding and Remodeling the Suppressive Tumor Immune Microenvironment in Head and Neck Cancer” |
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“The Role of Targeted Therapy in Head and Neck Cancers” |
“Molecular Targets for HPV-Related Head and Neck Cancer” |
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“Head and Neck Cancer: From Mechanisms to Therapeutic Approaches—Advances and Challenges” |
“Targeting Head and Neck Cancer: From Tumor Microenvironment to Therapy Resistance” |
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