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Special Issue "Biointerface Coatings for Biomaterials and Biomedical Applications"
A special issue of Coatings (ISSN 2079-6412).
Deadline for manuscript submissions: 15 November 2020.
Interests: biomolecular engineering; vapor-deposition; surface chemistry technique; biomedical coating technology
We would like to invite you to submit your work to this Special Issue on "Biointerface Coatings for Biomaterials and Biomedical Applications".
In addition to meeting the minimal requirement of biocompatibility, advanced biomaterials have acquired functions, allowing them to directly or indirectly influence specific biological environments. These modifications of biomaterials are generally achieved by establishing an interface layer, i.e., a biointerface coating, to deliver the desired functions. The design of a successful biointerface usually depends on criteria such as controlled presentation of functional biomolecules on the surface, low nonspecific protein adsorption, responsive actions toward external stimuli, multifunctionality, compatibility with micro- to nanofabrication, surface morphology or microstructures, biodegradability, and physical to chemical gradients. Many promising approaches have been realized by existing surface modification technologies based on both physical and chemical methods of rendering fabricated coatings on biomaterials, from basic self-assembly of molecules to top–down construction of bulk materials. Numerous methods exploit a complimentary and/or combinatorial strategy, paving the way to advanced and effective functional coatings for prospective biomaterials.
This Research Topic welcomes discussions related to biointerface coatings, including but not limited to the following:
(1) Molecularly self-assembled coatings;
(2) Surface modifications of coatings;
(3) Layer-by-layer coatings;
(4) Grafted coatings;
(5) Physically adsorbed coatings;
(6) Vapor-deposited coatings
(7) Coatings with chemical activity and/or physical properties;
(8) Innovations of novel coatings for biotechnological applications.
Encouraged forms of submission include original research papers, reviews, and perspective articles.
Prof. Dr. Hsien-Yeh Chen
Prof. Dr. Peng-Yuan Wang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Paper Type: Review
Title：A review of surface micropatterning as a powerful tool to manipulate stem cell functions
Authors: Naoki Kawazoe and Guoping Chen
Research Center for Functional Materials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan
Micropatterning techniques have found broad applications in biomedicine such as cell-based drug screening and point-of-care devices over the past decades, and, more recently tissue engineering scaffolds and organ-on-chips. Several techniques have been extensively developed and implemented to create precisely-controlled micropatterns, such as photolithography, microcontact imprinting, plasma/laser ablation, and stencil micropatterning. These techniques can also offer a powerful tool for basic studies in cell biology to investigate the impact of cell morphology, cell-cell interaction, and cell-material interaction on cell functions which include cell spreading, migration, proliferation, and differentiation. They can precisely control cell location and cell morphology at the single-cell scale on the substrate. Previous studies of cell culture on micropatterned surfaces have shown a number of interesting results on their functions that were not obtained in the conventional cell culture. In recent years, much attention has been paid to the manipulation of stem cells as a promising source for tissue engineering and regenerative medicine, because they are able to self-renew and differentiate into various specialized cell linages. This review highlights the recent advances of micropatterning for the manipulation of stem cell functions.