Progress and Prospects in Dental Materials and Endodontic Sciences

Dear Colleagues,

Endodontic and dental materials are fundamental to the success of modern clinical procedures. Over the past decade, significant progress has been made in developing materials with enhanced biological compatibility, mechanical durability, and therapeutic functionality. Innovations such as bioceramics, bioactive resins, nanomaterials, and smart delivery systems are transforming the way clinicians approach root canal therapy and restorative procedures.

These advancements not only improve clinical outcomes but also address long-standing challenges such as microbial leakage, post-treatment failures, and tissue regeneration. With an increasing focus on the chemical, mechanical, and biological properties of materials—alongside their cytotoxicity and genotoxicity—there is a growing need to consolidate research in this domain.

This Special Issue aims to present a focused collection of research that explores the development, characterization, and clinical performance of materials used in endodontics and dental restoration. It seeks to bridge basic material science with applied clinical outcomes, ensuring a multidisciplinary approach that aligns with the journal’s core focus on dental biomaterials, bioengineering, and therapeutic technologies.

The scope of this Special Issue includes, but is not limited to, the following topics:

• Novel root canal sealers and obturation materials;
• Bioceramic and bioactive materials in pulp therapy and repair;
• Mechanical and chemical characterization of dental materials;
• Biocompatibility assessments (cytotoxicity, genotoxicity);
• Antimicrobial and functional properties of dental materials;
• Nanomaterials, smart systems, and regenerative scaffolds;
• Surface modification and adhesive interactions with dentin;
• Long-term clinical performance and degradation of dental materials;
• Three-dimensional printing and digital workflows in restorative/endodontic applications.

We look forward to receiving your contributions.

Dr. Mateusz Radwanski
Prof. Dr. Monika Lukomska-Szymanska
Dr. Ewa Zmysłowska-Polakowska
Guest Editors

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