Cerebral Palsy in Children: Improving Quality of Life and Preventing Painful Musculoskeletal Disorders

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Orthopedics & Sports Medicine".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 882

Special Issue Editors


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Guest Editor
Department for Health Sciences, Medicine and Research, University for Continuing Education Krems, University Clinic Salzburg, and MOTIO, Vienna, Austria
Interests: paediatric orthopaedics; neuro-orthopaedics; child movement development; sensomotor and musculoskletal disorders; interdisiplinary screening and prevention of pain; improving quality of life in neuromotor diseases

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Guest Editor
1. Center for Health Sciences and Medicine, University for Continuing Education Krems, Krems, Austria
2. Department of Global Public Health, Karolinska Institutet, 171 77 Stockholm, Sweden
Interests: public health; physiotherapy; neuroorthopaedics; scientific publishing
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Special Issue Information

Dear Colleagues,

Cerebral palsy is the most common cause of movement impairment in childhood. It is a group of disorders caused by a developmental disorder or damage to the developing brain before, during or after birth, which, depending on their severity and localisation, are associated with various sensory and motor dysfunctions and changes in the shape of the locomotor organs. Disorders of walking, standing, sitting, grasping, seeing, hearing, sense of balance, exteroception and proprioception, postural control, communication, cognition, psyche, emotions and behaviour can lead to a considerable reduction in quality of life if pain, restriction of social participation, independence and mobility are present.

In children with cerebral palsy, lack of exercise, non-use and overuse syndromes regularly lead to secondary, initially reversible functional disorders of the sensorimotor system and the locomotor organs and cause musculoskeletal pain. If these are not treated at an early stage, irreversible misalignments of the locomotor system develop with changes in the muscular lever arms, fasciae, joint capsules and deformities as well as dislocations of the joints and bones. The resulting painful neurogenic hyperkyphosis, hyperlordosis, scoliosis, hip dislocations, joint contractures and hand and foot misalignments can usually only be treated palliatively at great expense.

This Special Issue about current research aims to give a deeper understanding of the pathogenesis and possibilities of preventing musculoskeletal pain in children with cerebral palsy.

Numerous studies in recent years have shown that the massive impairment of quality of life caused by these consequential damages can be significantly reduced by screening and secondary preventive measures. There is increasing evidence that new approaches, such as early treatment with verticalisation, movement, supra-threshold strength, coordination and endurance training, postural management and regular sensory input through senso-orthotics, including the stabilisation of unstable joints and exceeding the necessary minimum load and vascularisation of the tissues of the locomotor organs, as well as normal endorphin release, can contribute to pain relief, motivation, physiological sensorimotor development and improvement in quality of life.

We are looking for scientific papers that summarise the current state of knowledge and integrate our own experimental studies and clinical experience in order to provide practitioners and carers with guidance for the treatment of children with cerebral palsy.

Prof. Dr. Walter Strobl
Dr. Mathilde Sengölge
Guest Editors

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Keywords

  • cerebral palsy
  • quality of life
  • musculoskeletal pain
  • secondary prevention
  • neuromuscular gait disorders
  • neuromuscular hip dislocation
  • neuromuscular scoliosis
  • early treatment

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Published Papers (1 paper)

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12 pages, 236 KiB  
Article
Health-Related Quality of Life of Individuals with Physical Disabilities in Childhood
by Chris Church, Sana Patil, Stephanie Butler, Freeman Miller, Jose J. Salazar-Torres, Nancy Lennon, M. Wade Shrader, Maureen Donohoe, Faithe Kalisperis, W. G. Stuart Mackenzie and Louise Reid Nichols
Children 2025, 12(3), 365; https://doi.org/10.3390/children12030365 - 15 Mar 2025
Viewed by 528
Abstract
Background: The use of patient-reported outcomes is essential to understand and manage health-related quality of life (HRQOL) in youth with lifelong disabilities. This study evaluated HRQOL in youth with physical disorders and examined its relationship with mobility. Methods: We conducted an IRB-approved [...] Read more.
Background: The use of patient-reported outcomes is essential to understand and manage health-related quality of life (HRQOL) in youth with lifelong disabilities. This study evaluated HRQOL in youth with physical disorders and examined its relationship with mobility. Methods: We conducted an IRB-approved retrospective study in which we administered the parent-reported Pediatric Outcomes Data Collection Instrument (PODCI) and Gross Motor Function Measure section D (GMFM-D) to ambulatory youth aged 2–18 years with cerebral palsy (CP; Gross Motor Function Classification System II; n = 258), arthrogryposis (n = 138), achondroplasia (n = 102), and Morquio syndrome (n = 52) during clinical visits to a gait lab. The PODCI has two validated versions, child and adolescent, that assess perceptions about mobility, happiness, and pain. Differences in HRQOL between diagnostic groups, between age groups, and compared with non-disabled youth were examined using non-parametric tests. The relationship between GMFM-D and PODCI scores was analyzed with Pearson’s correlations. Results: Both age cohorts within all diagnosis groups demonstrated higher pain and lower mobility compared with non-disabled youth (p < 0.015). Happiness was lower for both age groups with CP and arthrogryposis, and for the child group with Morquio syndrome compared with non-disabled youth (p < 0.002). In diagnostic groups in both age spans, Global Function was higher (p < 0.0001) for those with achondroplasia compared with other groups. Despite functional differences, there were no significant differences between diagnostic groups in pain scores (p > 0.10). Happiness was lower in the group with CP compared with that with achondroplasia (p = 0.01). GMFM-D was related to PODCI mobility scores for all diagnoses (r = 0.31 to 0.79, p < 0.03) but was not correlated with happiness (r = −0.16 to 0.092; p > 0.14); GMFM-D and PODCI pain scores were associated only for the child group with achondroplasia (r = 0.355; p < 0.001). Conclusions: Significant limitations in HRQOL are present in youth with physical disabilities. Pain levels were higher than those of non-disabled youth, but pain was not related to lower motor function. Happiness was not related to gross motor function, suggesting the need to examine other factors when mental health concerns are present in youth with disabilities. Full article
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