Mast Cells in Health and Diseases

Dear Colleagues,

Mast cells leave the bone marrow as progenitors and reach their final maturation within peripheral tissues. Mast cells play a central role in IgE-dependent allergic diseases such as asthma and rhinoconjunctivitis through the release of a variety of vasoactive and bronchospastic autacoid mediators and functionally diverse proteases, chemokines and cytokines. Mast cells play an important role in innate immunity, angiogenesis and tissue repairing through non-IgE-dependent stimulation. In this Topical Collection of Cells, I invite you to contribute, either in the form of original research articles, reviews or shorter perspective articles on all aspects related to the theme of “Mast Cells in Health and Diseases”. Expert articles describing new roles of mast cells in health and diseases, new evidence of mast cell differentiation and maturation, and mast cell heterogeneity are welcome.

Dr. Yoshimichi Okayama
Collection Editor

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