Cells

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Cardiometabolic Pathophysiology and Treatment

edited by

Paolo Magni

and

Carla Perego

submission deadline 30 Sep 2026 | Viewed by 26 | Submission Open

Keywords: insulin resistance; immunometabolism; low-grade chronic inflammation; cardiovascular diseases; obesity; type 2 diabetes mellitus; adipose/adipocyte dysfunction; dyslipidemia; atherosclerosis; metabolic-associated steatotic liver disease

(This special issue belongs to the Section Cellular Metabolism)

New Advances in Proteomics for Understanding Health and Disease

edited by

Syed Azmal Ali

submission deadline 10 Oct 2026 | Viewed by 10 | Submission Open

Keywords: mass spectrometry; single-cell proteomics; plasma proteomics; systems biology; cancer biology; health and disease; precision medicine; protein networks; clinical proteomics; multi-omics integration

(This special issue belongs to the Section Cell Methods)

Advances in Muscle Research in Health and Disease—2nd Edition

edited by

Wan Lee

submission deadline 20 Oct 2026 | 4 articles | Viewed by 8817 | Submission Open

Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target

(This special issue belongs to the Section Tissues and Organs)

Caveolae Function in Cell Membrane Dynamics and Signal Transduction

edited by

Alessio D'Alessio

and

Antonio Filippini

submission deadline 25 Oct 2026 | Viewed by 148 | Submission Open

Keywords: caveolae; caveolin and cavin proteins; plasma membrane organization; endocytosis and vesicular trafficking; mechanotransduction; lipid rafts and cholesterol metabolism; signal transduction; vascular biology and angiogenesis; cancer cell biology; membrane remodeling in disease

Cellular and Molecular Mechanisms in Bone and Cartilage Damage and Regeneration

edited by

Philippe Hernigou

submission deadline 31 Oct 2026 | 7 articles | Viewed by 13175 | Submission Open

Keywords: bone morphogenic proteins (BMPs); bone union with cell therapy; advances in stem cell therapies for fracture non-union and cartilage regeneration; novel cell-based therapies for cartilage repair; functional of collagen/PLA scaffolds in cartilage regeneration; regeneration and revascularization of bone osteonecrosis; evaluation of osteonecrosis regeneration with MRI and histology; and arteriography; identification and validation of new cartilage biomarkers; diaphyseal regeneration with callostasis; union with the membrane technique

(This special issue belongs to the Section Cellular Pathology)

Immunoregulation in Cardiovascular Disease

edited by

Hong Wang

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1792 | Submission Open

Keywords: cardiovascular disease (CVD); immunoregulation; inflammation; immune cells; immune mediators; immunomodulatory therapies; biomarkers; epigenetics; microbiome; cellular methods/technologies

Neurotoxicity: Focusing on Molecular and Cellular Mechanisms

edited by

Pablo Martín-Vasallo

, Manuel José Morales and

Rita Martín-Ramírez

submission deadline 31 Oct 2026 | Viewed by 84 | Submission Open

Keywords: neurotoxicity; neuroinflammation; neurodegeneration; chemotherapy-induced neuropathy; neuroprotection; neuronal injury

Interactions Between Gut Microbiota and Epigenetic Markers in Health and Disease

edited by

Shabnam Nohesara

submission deadline 31 Oct 2026 | Viewed by 79 | Submission Open

Keywords: gut microbiome; epigenetic marks; cancer; metabolic diseases; neuropsychiatric disorders; inflammatory diseases; infectious diseases; cardiovascular diseases; probiotics; prebiotics

(This special issue belongs to the Section Cell and Gene Therapy)

Mechanobiological Regulation of Fibroblast-to-Myofibroblast Phenotype Transition

edited by Mirko D’urso and

Nicholas A. Kurniawan

submission deadline 31 Oct 2026 | Viewed by 57 | Submission Open

Keywords: fibroblasts; myofibroblasts; mechanotransduction; extracellular matrix; fibrosis; tissue remodeling; mechanobiology

(This special issue belongs to the Section Cell Microenvironment)

Nucleic Acids and Their Binding Partners: Structural and Mechanistic Insights

edited by

Rashmi Panigrahi

submission deadline 31 Oct 2026 | Viewed by 37 | Submission Open

Keywords: cryo-EM; NMR; AFM; molecular dynamics; nucleic acids; nucleic acid-protein complexes

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Role of Inflammasomes in Neurological Disorders

edited by

Juan Pablo de Rivero Vaccari

submission deadline 1 Nov 2026 | Viewed by 67 | Submission Open

Keywords: inflammasome; pyroptosis; caspase-1; ASC specks; IL-1beta; PANoptosis; CNS injury; neurodegenerative diseases; biomarkers; Alzheimer’ s disease; Parkinson’ s disease; multiple sclerosis; amyotrophic lateral sclerosis

(This special issue belongs to the Section Cellular Neuroscience)

Methane Biosynthesis

edited by

Divya Prakash

, James Ferry and

Shikha Singh Chauhan

submission deadline 10 Nov 2026 | Viewed by 225 | Submission Open

Keywords: methane; methanogenesis; methanogens; carbon cycle; gut microbiota; energy conservation; human diseases

Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy

edited by Behzad M. Toosi and

Andrew Freywald

submission deadline 30 Nov 2026 | 2 articles | Viewed by 5268 | Submission Open

Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology

(This special issue belongs to the Section Cell Microenvironment)

Mechanisms of Transcriptional Regulation in Disease: From Chromatin Dynamics to Therapeutic Innovation

edited by Valentina Caputo and Joana R. Costa

submission deadline 30 Nov 2026 | Viewed by 43 | Submission Open

Keywords: transcription regulation; epigenomics; multi-omics; non-coding genome; chromatin architecture/dynamics; enhancers

(This special issue belongs to the Section Cell and Gene Therapy)

Molecular Mechanisms of Asthmatic Airway Inflammation

edited by

Pawan Sharma

submission deadline 30 Nov 2026 | Viewed by 20 | Submission Open

Keywords: asthma; airway inflammation; airway smooth muscle; airway remodeling; immune signaling; cytokines and chemokines; cell signaling; inflammatory mechanisms; airway epithelial cells

(This special issue belongs to the Section Cellular Immunology)

Cellular Pathology: Emerging Discoveries and Perspectives in the USA

edited by

Mohammed S. Razzaque

submission deadline 31 Dec 2026 | 2 articles | Viewed by 8151 | Submission Open

Keywords: cellular pathology; diseases; mechanisms

(This special issue belongs to the Section Cellular Pathology)

Current Status and Future Challenges of Liquid Biopsy—2nd Edition

edited by

Kenichi Suda

and

Shuta Ohara

submission deadline 1 Oct 2027 | Viewed by 237 | Submission Open

Keywords: minimal residual disease (MRD); ctDNA; cfDNA; heterogeneity; comprehensive genomic profiling; biomarker; diagnosis; personalization; prognostic marker

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