Sugars on Cell Surfaces and Their Biological Purposes

Dear Colleagues,

Every cell is surrounded by a plasma membrane, which separates the cell from the extracellular environment and controls the exchange of substances. The outer leaflet of this plasma membrane contains numerous glycosylated proteins and lipids. This dense meshwork of glycoconjugates forms the so-called cellular glycocalyx. Since the glycans (sugars) of the cell surface reach far out into the extracellular space, they directly influence cellular processes, such as cell recognition, signal transduction or cell migration.

The aim of this Special Issue is to enlighten the role of these sugars in all aspects of physiological or pathophysiological mechanisms. We are looking for cutting-edge research demonstrating the role of sugars on the cell surface.

Topics of interest may include:

• Glyco-engineering of cell surfaces
• Non-enzymatic glycation of cell surface receptors
• The role of glycans during development
• Glycans and cancer
• Neuroglycobiology
• Glycoimmunology
• Glycan mediated host−pathogen interactions

Articles will be peer-reviewed and published in the open access journal Cells (Impact Factor 5.656, ISSN 2073-4409). We look forward to your contributions.

Dr. Sebastian P. Galuska
Prof. Dr. Rüdiger Horstkorte
Guest Editors

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