Special Issue "150 Years of Motor Endplate: Molecules, Cells, and Relevance of a Model Synapse"

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 30 June 2019

Special Issue Editor

Guest Editor
Prof. Dr. Rüdiger Rudolf

1. Institute of Molecular and Cell Biology, Faculty of Biotechnology, Mannheim University of Applied Sciences, Mannheim, Germany
2. Interdisciplinary Center for Neuroscience, Heidelberg University, Heidelberg, Germany
3. Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany
Website | E-Mail
Interests: neuromuscular junction

Special Issue Information

Dear Colleagues,

More than 150 years after the terms ‘plaques nerveuses terminales’ and ‘motorische Endplatte’ were coined by Charles Rouget and Wilhelm Krause, respectively, the neuromuscular synapse continues to be crucial for the musculoskeletal and neural sciences. Having always served as a model in terms of morphological and molecular configuration of chemical synapses, recent research has renewed an interest in the involvement of the motor endplate in general systemic functions of muscle beyond inducing contraction. Along these lines, the endplate has lately also attracted increasing attention with respect to its role in pathophysiology and aging.

This Special Issue of Cells will focus on the progress in understanding the molecular and cellular frameworks that regulate and mediate formation, maintenance, and repair of the motor endplate in normal physiology and upon pathological conditions. Further, it will address consequences of these insights on treatment of neuromuscular diseases and muscle wasting conditions.

Dr. Rüdiger Rudolf
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neuromuscular synapse
  • muscle innervation
  • neuromuscular disorders
  • muscle wasting
  • muscle regeneration

Published Papers

This special issue is now open for submission.
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