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Special Issue "Innate-Acquired Linkage in Immunotherapy"
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Signaling".
Deadline for manuscript submissions: closed (15 August 2020) | Viewed by 27035
Special Issue Editor
Interests: dendritic cells; toll-like receptor; cool adjuvant (immune-enhancer without inflammation)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
A variety of immune cells join the maintenance of homeostasis against environmental emergency and happenings. The immune system is categorized into innate and acquired systems, and vertebrates including humans possess a network constituting innate–acquired linkage. T lymphocyte proliferation and activation is rooted in dendritic cell/macrophage signal in the context of innate pattern sensing. Antigen-presenting dendritic cells consist of unique subsets and enhance T cell proliferation and antibody production by B cells. Pattern-sensing renders inflammatory profiles multifarious in a cell type-specific manner, in some cases reaching prolonged inflammation, resulting in chronic diseases. Thus, the regulation of excess inflammatory response is indispensable for life health. Many cell types have their own unique innate/acquired response depending on environmental factors. However, the mechanisms whereby the immune system makes homeostasis in disease states remain largely to be elucidated. Immune-enhancers called adjuvant, blockades of checkpoint inhibitors, dying cells, and damage-associated molecular patterns (DAMP) all accelerate inflammatory status in their environmental context. The purpose of this Special Issue on ‘Innate–Acquired Linkage in Immunotherapy’ is to develop more understanding of immune regulation in inflammation-related diseases.
Prof. Tsukasa Seya
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- dendritic cells
- toll-like receptor
- checkpoint inhibitor
- innate lymphocyte
- dying cell alarm
Related Special Issue
- Innate-Acquired Linkage in Immunotherapy—Series II in Cells (1 article)