Evolution of Epigenetic Mechanisms and Signatures

Dear Colleagues,

For many years epigenetics has been considered a hot topic in basic and applied biosciences. Many mechanisms have been elucidated governing genome activity regulation at the levels of chromatin organization, the transcription of DNA, RNA stability and translation. These include but are not limited to DNA methylation and hydroxmethylation; histone modifications; and various types of non-coding RNAs like circular RNAs, small interfering RNAs, and micro RNA machinery. Numerous applications have been found in fundamental studies, bioengineering, and molecular diagnostics.

Many epigenetic mechanisms have been investigated in detail in such biologically distinct objects as mammals (human, mouse), teleosts (zebrafish), insects (drosophila), nematodes (C.elegans), and plants (Arabidopsis). This has been immensely enhanced by the recent progress in massive parallel screening technologies such as next-generation sequencing and modern proteomic approaches. Rich materials have been accumulated and the time has arrived to take a panoramic view of epigenetic mechanisms in the context of molecular evolution. In this Special Issue, the authors are invited to submit all formats of manuscripts dealing with the evolutionary aspects of epigenetic mechanisms. Both bioinformatic and experimental research papers and reviews will be accepted.

Dr. Anton Buzdin
Dr. Alla Kalmykova
Guest Editor

Manuscript Submission Information

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