The Molecular and Cellular Basis of Retinal Diseases

Dear Colleagues,

Recent success in the treatment of hereditary retinal disease caused by defects in the RPE65 gene and the FDA approval of this treatment has established the importance of the study of animal models and the translational impact of these research findings. This success has sparked an intense interest in the development of animal models for other hereditary eye diseases and has led to a dramatic increase in clinical trials in this area.

This Special Issue will focus on studies of new animal models of hereditary retinal degeneration and highlight the current knowledge in the field regarding the basic metabolic processes and biochemical pathways that offer promising new therapeutic targets for successful intervention in such retinal diseases. We hope that the combination of original papers and focused reviews will provide a useful resource for advancing an understanding of the molecular and cellular basis of retinal diseases, which will enlighten researchers currently in the field and entice some others to take a closer look at the great potential for discovery and intervention in hereditary diseases of the retina.

We look forward to your contributions.

Prof. Steven J Pittler
Prof. Steven J. Fliesler
Guest Editors

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