Molecular Mechanism and Therapeutic Opportunities of Breast Cancer
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 10 November 2025 | Viewed by 1111
Special Issue Editor
Interests: biochemistry; GPCR signaling; molecular pharmacology; molecular mechanisms of pharmacological action; cell biology; cancer research; drug design
Special Issue Information
Dear Colleagues,
Breast cancer is one of the most frequent cancers worldwide and is characterized by multifactorial etiology and genetic heterogeneity. Molecular mechanisms involved in its pathogenesis include imbalances in cell signaling, metabolism, and stress responses, as well as gene dysfunction. Recent studies have identified new target molecules such as hormone receptors, human epidermal growth factor receptors, and molecular pathways related to cancer cell survival and metastasis. These findings have led to innovative therapeutic strategies, such as targeted antibody therapies, macromolecular and micromolecular inhibitors, and immunotherapies. Personalized medicine based on genomic and tumor profiling offers promising prospects for improving prognosis and reducing side effects. But tackling tumor resistance to treatment and understanding its mechanics is a far greater challenge. As part of the Special Issue, papers could be published that focus on topics such as novel molecular mechanisms involved in the development and progression of breast cancer, targeted therapies, molecular biomarkers, use of genomic analysis for personalized therapy and treatment decisions, immunotherapy, and mechanisms of resistance development, as well as issues related to drug resistance and relapse, and innovative methods for the diagnosis and monitoring of breast cancer.
Dr. Athanasios A. Panagiotopoulos
Guest Editor
Manuscript Submission Information
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Keywords
- breast cancer
- molecular mechanisms
- targeted therapy
- genomic profiling
- hormone receptors
- tumor microenvironment
- immunotherapy
- drug resistance
- metastasis
- precision medicine
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