Special Issue "Role of T Cells from Adaptive Immune Responses to Therapies"

Dear Colleagues,

We are frequently exposed to external microorganisms and pathogens such as viruses, fungi and bacteria. Innate and adoptive immune responses are our vital defense system. T cells are the backbone of our adaptive immune system.From bone morrow to the thymus, T cells complete their development and differentiation process before entering the blood to be carried throughout the whole body's circulation and lymphoid tissues. T cells are sensitive to specific antigens presented by cells during infection. T cells are a major population of the adaptive immune system. During immune responses, T cells play a crucial role in identifying external microorganism such as bacteria and viruses that can cause disease as well as helping B cells to eliminate pathogens. Depending on their specific phenotype, T cells and their subtypes modulates immune responses in inflammatory and autoimmune diseases. Such function highlights the importance of T cells to be used for therapy. Using the adoptive transfer of T cells and their subpopulations becomes innovative as a treatment for different immune or inflammatory diseases. This Special Issue is an Open Access forum for collecting specific and original scientific studies and review articles targeting the enrichment of knowledge in the area of T cell responses and function during infection, inflammatory and autoimmune disease progress. We aim to prepare a solid resource of innovative research articles on the role of T cells in adoptive immunity and therapeutic fields.  Suggested potential topics may be: new T cell variants/functions; the role of T cells in new diseases; immunotherapy; CAR T cells; the adoptive transfer of T cells and subtypes; and proteomic characteristics of T cells during inflammation or immune responses.

Dr. Tilili Barhoumi
Prof. Dr. Stephen Todryk
Guest Editors

Manuscript Submission Information

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• T cells
• inflammation
• immune system
• CAR T cells
• immunotherapy
• adoptive transfer
• cell therapy
• immune checkpoint inhibitors