Special Issue "Role of T Cells from Adaptive Immune Responses to Therapies"

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".

Deadline for manuscript submissions: 31 January 2024 | Viewed by 206

Special Issue Editors

1. Medical Research Core Facility and Platforms, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh 11481, Saudi Arabia
2. King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
Interests: innate immunity in hypertension; atherosclerosis; hypertension; vascular biology; metabolic/nutritional physiology; diabetes; obesity; cell biology; inflammation; oxidative stress; T cells
1. Faculty of Health & Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK
2. Translational & Clinical Research Institute, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
Interests: T cells; anti-microbial immunity; immune memory; biomarkers
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are frequently exposed to external microorganisms and pathogens such as viruses, fungi and bacteria. Innate and adoptive immune responses are our vital defense system. T cells are the backbone of our adaptive immune system.From bone morrow to the thymus, T cells complete their development and differentiation process before entering the blood to be carried throughout the whole body's circulation and lymphoid tissues. T cells are sensitive to specific antigens presented by cells during infection. T cells are a major population of the adaptive immune system. During immune responses, T cells play a crucial role in identifying external microorganism such as bacteria and viruses that can cause disease as well as helping B cells to eliminate pathogens. Depending on their specific phenotype, T cells and their subtypes modulates immune responses in inflammatory and autoimmune diseases. Such function highlights the importance of T cells to be used for therapy. Using the adoptive transfer of T cells and their subpopulations becomes innovative as a treatment for different immune or inflammatory diseases. This Special Issue is an Open Access forum for collecting specific and original scientific studies and review articles targeting the enrichment of knowledge in the area of T cell responses and function during infection, inflammatory and autoimmune disease progress. We aim to prepare a solid resource of innovative research articles on the role of T cells in adoptive immunity and therapeutic fields.  Suggested potential topics may be: new T cell variants/functions; the role of T cells in new diseases; immunotherapy; CAR T cells; the adoptive transfer of T cells and subtypes; and proteomic characteristics of T cells during inflammation or immune responses.

Dr. Tilili Barhoumi
Prof. Dr. Stephen Todryk
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • T cells
  • inflammation
  • immune system
  • CAR T cells
  • immunotherapy
  • adoptive transfer
  • cell therapy
  • immune checkpoint inhibitors

Published Papers

This special issue is now open for submission.
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