Novel Insight into Endothelial Function and Atherosclerosis

Dear Colleagues,

Atherosclerotic disease is one of the most common and serious problems of modern medicine. It is known as a chronic inflammatory disease involving arteries; however, it is much more than that and involves from metabolism to immunology, and from hemorheology to hemodynamics, each of these aspects contributes to its development. Endothelial function plays a crucial role in the development and progression of atherosclerosis. The endothelium, the inner layer of the blood vessel wall, regulates vascular homeostasis, primarily through the production of vasodilatory and anti-inflammatory agents, among them being nitric oxide (NO). If the role of the endothelium in the process of atherosclerosis is of extreme importance in this research area, it is yet poorly considered as a possible target. A deeper understanding of the mechanisms behind endothelial dysfunction, from different points of view, could certainly help to cure atherosclerosis.

This Special Issue aims to provide a collection of the current knowledge and novel insights into endothelial function and atherosclerosis.

We are pleased to invite you as a recognized expert in the field to contribute original articles, communications, and reviews covering the entire field of endothelial function and atherosclerosis, including (but not limited to) the following:

• Immunometabolism and atherosclerosis;
• The novel biomarkers of endothelial dysfunction and atherosclerosis;
• The role of hemorheology and hemodynamics in atherosclerosis;
• The endothelial cell dysfunction and pathobiology of atherosclerosis;
• Advances in the assessment of endothelial function;
• Vascular biology and microcirculation.

We look forward to receiving your contributions.

Dr. Antonio Cutruzzolà
Dr. Alessandro Salatino
Prof. Dr. Concetta Irace
Guest Editors

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