Special Issue "Insulin-Degrading Enzyme in Health and Disease"
Deadline for manuscript submissions: closed (15 March 2022) | Viewed by 17371
Interests: diabetes mellitus; insulin resistance; endocrine pancreas; insulin-degrading enzyme
Interests: obesity; diabetes; cardiovascular disease; metabolic syndrome; endocrinology; insulin resistance; insulin clearance; metabolism
Special Issues, Collections and Topics in MDPI journals
Insulin-degrading enzyme (IDE) is an endopeptidase that degrades insulin and amyloid β (Aβ). The Ide gene has been associated with type-2 diabetes mellitus (DM2), and it is a molecular link between DM2 and Alzheimer´s disease (AD). The physiological role(s) of IDE in glucose/insulin homeostasis is very controversial and its potential therapeutic benefit for DM2 and AD remains not completely understood. This Special Issue aims to gather expert articles on the structure, function, and regulation of IDE in physiological and pathophysiological conditions. I therefore invite you to submit original research articles or reviews.
Prof. Dr. Irene Cozar-Castellano
Dr. German Perdomo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- insulin-degrading enzyme
- insulin degradation
- insulin clearance
- Abeta degradation
- diabetes mellitus
- Alzheimer's disease